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'''Catherine Dulac''' is a [[French Americans|French–American]] [[Molecular biology|molecular biologist]] and [[Neuroscience|neuroscientist]]. She is a [[professor]] at the Department of [[Molecular biology|Molecular]] and [[Cell biology|Cellular]] Biology of [[Harvard University]] and, since 2022,<ref>{{cite news |title=Dulac, Sampson, and Sharpe honored with highest distinction for a faculty member |url=https://news.harvard.edu/gazette/story/2022/11/harvard-names-three-new-university-professors/ |access-date=February 7, 2024 |work=[[Harvard University#Harvard University Gazette|The Harvard Gazette]] |date=November 28, 2022 |archive-url=https://web.archive.org/web/20240207030616/https://news.harvard.edu/gazette/story/2022/11/harvard-names-three-new-university-professors/ |archive-date=February 7, 2024}}</ref> has been the current [[List of University Professors at Harvard University|Samuel W. Morris University Professor]].<ref>{{cite web |title=Catherine Dulac |url=https://www.mcb.harvard.edu/directory/catherine-dulac/ |publisher=Department of Molecular and Cellular Biology, Harvard University |access-date=February 6, 2024 |archive-url=https://web.archive.org/web/20240206093003/https://www.mcb.harvard.edu/directory/catherine-dulac/ |archive-date=February 6, 2024}}</ref> Prior to her appointment as University Professor, she was the Higgins Professor of Molecular and Cellular Biology (from 2006)<ref name="cv"/> and the Lee and Ezpeleta Professor of Arts and Sciences (from 2018)<ref>{{cite news |last1=Li |first1=Katelyn X. |title=Four Harvard Faculty Awarded Arts and Sciences Professorships |url=https://www.thecrimson.com/article/2018/4/19/new-arts-and-sciences-professorships/ |access-date=February 14, 2024 |work=[[The Harvard Crimson]] |date=April 19, 2018 |archive-url=http://archive.today/2024.02.14-015456/https://www.thecrimson.com/article/2018/4/19/new-arts-and-sciences-professorships/ |archive-date=February 14, 2024}}</ref> in the [[Harvard Faculty of Arts and Sciences|Faculty of Arts and Sciences]] at Harvard University. |
'''Catherine Dulac''' is a [[French Americans|French–American]] [[Molecular biology|molecular biologist]] and [[Neuroscience|neuroscientist]]. She is a [[professor]] at the Department of [[Molecular biology|Molecular]] and [[Cell biology|Cellular]] Biology of [[Harvard University]] and, since 2022,<ref>{{cite news |title=Dulac, Sampson, and Sharpe honored with highest distinction for a faculty member |url=https://news.harvard.edu/gazette/story/2022/11/harvard-names-three-new-university-professors/ |access-date=February 7, 2024 |work=[[Harvard University#Harvard University Gazette|The Harvard Gazette]] |date=November 28, 2022 |archive-url=https://web.archive.org/web/20240207030616/https://news.harvard.edu/gazette/story/2022/11/harvard-names-three-new-university-professors/ |archive-date=February 7, 2024}}</ref> has been the current [[List of University Professors at Harvard University|Samuel W. Morris University Professor]].<ref name="morris">{{cite web |title=Catherine Dulac |url=https://www.mcb.harvard.edu/directory/catherine-dulac/ |publisher=Department of Molecular and Cellular Biology, Harvard University |access-date=February 6, 2024 |archive-url=https://web.archive.org/web/20240206093003/https://www.mcb.harvard.edu/directory/catherine-dulac/ |archive-date=February 6, 2024}}</ref> Prior to her appointment as University Professor, she was the Higgins Professor of Molecular and Cellular Biology (from 2006)<ref name="cv"/> and the Lee and Ezpeleta Professor of Arts and Sciences (from 2018)<ref name="leeezpeleta">{{cite news |last1=Li |first1=Katelyn X. |title=Four Harvard Faculty Awarded Arts and Sciences Professorships |url=https://www.thecrimson.com/article/2018/4/19/new-arts-and-sciences-professorships/ |access-date=February 14, 2024 |work=[[The Harvard Crimson]] |date=April 19, 2018 |archive-url=http://archive.today/2024.02.14-015456/https://www.thecrimson.com/article/2018/4/19/new-arts-and-sciences-professorships/ |archive-date=February 14, 2024}}</ref> in the [[Harvard Faculty of Arts and Sciences|Faculty of Arts and Sciences]] at Harvard University. |
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== Early life and education == |
== Early life and education == |
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In 1996, Dulac joined the Department of [[Molecular biology|Molecular]] and [[Cell biology|Cellular]] Biology of [[Harvard University]] as an [[assistant professor]],<ref name="cv"/><ref>{{cite web |title=Molecular and neural architecture of circuits underlying social behavior in the mouse |url=https://www.sfari.org/event/molecular-and-neural-architecture-of-circuits-underlying-social-behavior-in-the-mouse/ |publisher=[[Simons Foundation]] |access-date=February 15, 2024 |archive-url=https://web.archive.org/web/20240215090945/https://www.sfari.org/event/molecular-and-neural-architecture-of-circuits-underlying-social-behavior-in-the-mouse/ |archive-date=February 15, 2024}}</ref> She was promoted to [[associate professor]] in 2000 and then [[Professor|full professor]] in 2001.<ref name="cv"/> She was the department chair between 2007 and 2013.<ref>{{cite news |first1=Charles |last1=Jennings |url=https://news.mit.edu/2017/mcgovern-institute-awards-2017-scolnick-prize-catherine-dulac-0213 |title=McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac |work=[[MIT News]] |access-date=February 9, 2024 |archive-url=https://web.archive.org/web/20240209032051/https://news.mit.edu/2017/mcgovern-institute-awards-2017-scolnick-prize-catherine-dulac-0213 |archive-date=February 9, 2024}}</ref> |
In 1996, Dulac joined the Department of [[Molecular biology|Molecular]] and [[Cell biology|Cellular]] Biology of [[Harvard University]] as an [[assistant professor]],<ref name="cv"/><ref>{{cite web |title=Molecular and neural architecture of circuits underlying social behavior in the mouse |url=https://www.sfari.org/event/molecular-and-neural-architecture-of-circuits-underlying-social-behavior-in-the-mouse/ |publisher=[[Simons Foundation]] |access-date=February 15, 2024 |archive-url=https://web.archive.org/web/20240215090945/https://www.sfari.org/event/molecular-and-neural-architecture-of-circuits-underlying-social-behavior-in-the-mouse/ |archive-date=February 15, 2024}}</ref> She was promoted to [[associate professor]] in 2000 and then [[Professor|full professor]] in 2001.<ref name="cv"/> She was the department chair between 2007 and 2013.<ref>{{cite news |first1=Charles |last1=Jennings |url=https://news.mit.edu/2017/mcgovern-institute-awards-2017-scolnick-prize-catherine-dulac-0213 |title=McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac |work=[[MIT News]] |access-date=February 9, 2024 |archive-url=https://web.archive.org/web/20240209032051/https://news.mit.edu/2017/mcgovern-institute-awards-2017-scolnick-prize-catherine-dulac-0213 |archive-date=February 9, 2024}}</ref> |
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Dulac was appointed Higgins Professor of Molecular and Cellular Biology in 2006<ref name="cv"/> and then Lee and Ezpeleta Professor of Arts and Sciences, a five-year position, in 2018.<ref>{{cite news |last1=Simon |first1=Clea |title=Giving to the next generation |url=https://news.harvard.edu/gazette/story/2019/05/harvard-professor-pays-it-forward-by-creating-fellowship-for-student/ |access-date=February 18, 2024 |work=The Harvard Gazette |date=May 23, 2019 |archive-url= |archive-date=February 18, 2024}}</ref> In 2022, she was conferred with the highest honor for a Harvard [[academic staff]], having been named one of the [[List of University Professors at Harvard University|University Professors]], the Samuel W. Morris University Professor.<ref>{{cite magazine |title=Three New University Professors |url=https://www.harvardmagazine.com/2022/11/harvard-three-new-university-professors |access-date=February 18, 2024 |magazine=Harvard Magazine |date=November 30, 2022 |archive-url=https://web.archive.org/web/20240218143517/https://www.harvardmagazine.com/2022/11/harvard-three-new-university-professors |archive-date=February 18, 2024}}</ref><ref>{{cite news |last1=Kim |first1=Ariel H. |last2=Xu |first2=Meimei |title=Three Harvard Scholars Named University Professors, Highest Faculty Distinction |url=https://www.thecrimson.com/article/2022/11/30/three-named-university-professors/ |access-date=February 18, 2024 |work=The Harvard Crimson |date=November 30, 2022 |archive-url=http://archive.today/2024.02.18-144024/https://www.thecrimson.com/article/2022/11/30/three-named-university-professors/ |archive-date=February 18, 2024}}</ref> |
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== Research == |
== Research == |
Revision as of 14:43, 18 February 2024
Catherine Dulac | |
---|---|
Born | [4] | February 11, 1963
Education | École Normale Supérieure (BSc) Institut d'Embryologie cellulaire et moléculaire (Institute of Cellular and Molecular Embryology) (PhD) Pierre and Marie Curie University(PhD)[1][6] |
Known for | Mammalian pheromones Parental brain regulation Research in neuroscience of sex differences Genomic imprinting |
Awards | Richard Lounsbery Award Breakthrough Prize in Life Sciences |
Scientific career | |
Fields | Molecular biology Neuroscience |
Institutions | Columbia University Harvard University Howard Hughes Medical Institute[1] |
Thesis | Etude de la differenciation des cellules gliales dans le systeme nerveux peripherique (Molecular and cellular study of glial cell differentiation in the peripheral nervous system) (1991) |
Doctoral advisor | Nicole Marthe Le Douarin[2] |
Other academic advisors | Richard Axel[3] |
Catherine Dulac is a French–American molecular biologist and neuroscientist. She is a professor at the Department of Molecular and Cellular Biology of Harvard University and, since 2022,[7] has been the current Samuel W. Morris University Professor.[8] Prior to her appointment as University Professor, she was the Higgins Professor of Molecular and Cellular Biology (from 2006)[1] and the Lee and Ezpeleta Professor of Arts and Sciences (from 2018)[9] in the Faculty of Arts and Sciences at Harvard University.
Early life and education
Dulac grew up in Montpellier, France. Her parents were academics and researchers in the humanities. [10] She entered the École Normale Supérieure in 1982,[11] graduating with a BSc 4 years later.[1]
She then conducted her PhD research under Nicole Marthe Le Douarin at the Institut d'Embryologie cellulaire et moléculaire (Institute of Cellular and Molecular Embryology) in Nogent-sur-Marne,[1] which was affiliated to both Collège de France and the French National Centre for Scientific Research,[12] and defended her PhD thesis at the Pierre and Marie Curie University in Paris in 1991.[6] She stayed at the Institut d'Embryologie cellulaire et moléculaire until 1992.[1]
Career
After her PhD, in 1993, Dulac went to Columbia University as a postdoctoral fellow in Richard Axel's group. One of the reasons for moving to the United States despite not speaking English was her desire to work on mice, which was a model organism, unlike chicken embryos that she had been working on.[2][10]
In 1996, Dulac joined the Department of Molecular and Cellular Biology of Harvard University as an assistant professor,[1][13] She was promoted to associate professor in 2000 and then full professor in 2001.[1] She was the department chair between 2007 and 2013.[14]
Dulac was appointed Higgins Professor of Molecular and Cellular Biology in 2006[1] and then Lee and Ezpeleta Professor of Arts and Sciences, a five-year position, in 2018.[15] In 2022, she was conferred with the highest honor for a Harvard academic staff, having been named one of the University Professors, the Samuel W. Morris University Professor.[16][17]
Research
Dulac has done extensive research on the molecular biology of olfactory signaling in mammals, particularly including pheromones,[18] and downstream brain circuits controlling sex-specific behaviors.[19] She developed a novel screening strategy based on screening cDNA libraries from single neurons and a new method of cloning genes from single neurons. As a postdoc, Dulac discovered the first family of mammalian pheromone receptors when working in Nobel laureate Richard Axel's laboratory at Columbia University.[20]
Publications
Notable papers
- Wu, Zheng; Autry, Anita E.; Bergan, Joseph F.; Watabe-Uchida, Mitsuko; Dulac, Catherine G. (2014). "Galanin neurons in the medial preoptic area govern parental behaviour". Nature. 509 (7500). Springer Science and Business Media LLC: 325–330. Bibcode:2014Natur.509..325W. doi:10.1038/nature13307. ISSN 0028-0836. PMC 4105201. PMID 24828191.
- Bergan, Joseph F; Ben-Shaul, Yoram; Dulac, Catherine (June 3, 2014). "Sex-specific processing of social cues in the medial amygdala". eLife. 3. eLife Sciences Publications, Ltd: e02743. doi:10.7554/elife.02743. ISSN 2050-084X. PMC 4038839. PMID 24894465.
- Gregg, C.; Zhang, J.; Butler, J. E.; Haig, D.; Dulac, C. (July 8, 2010). "Sex-Specific Parent-of-Origin Allelic Expression in the Mouse Brain". Science. 329 (5992). American Association for the Advancement of Science (AAAS): 682–685. Bibcode:2010Sci...329..682G. doi:10.1126/science.1190831. ISSN 0036-8075. PMC 2997643. PMID 20616234.
- Kimchi, Tali; Xu, Jennings; Dulac, Catherine (2007). "A functional circuit underlying male sexual behaviour in the female mouse brain". Nature. 448 (7157). Springer Science and Business Media LLC: 1009–1014. Bibcode:2007Natur.448.1009K. doi:10.1038/nature06089. ISSN 0028-0836. PMID 17676034. S2CID 4427883.
- Tietjen, Ian; Rihel, Jason M.; Cao, Yanxiang; Koentges, Georgy; Zakhary, Lisa; Dulac, Catherine (2003). "Single-Cell Transcriptional Analysis of Neuronal Progenitors". Neuron. 38 (2). Elsevier BV: 161–175. doi:10.1016/s0896-6273(03)00229-0. ISSN 0896-6273. PMID 12718852. S2CID 5872628.
- Pantages, Erica; Dulac, Catherine (2000). "A Novel Family of Candidate Pheromone Receptors in Mammals". Neuron. 28 (3). Elsevier BV: 835–845. doi:10.1016/s0896-6273(00)00157-4. ISSN 0896-6273. PMID 11163270. S2CID 15023062.
- Liman, E. R.; Corey, D. P.; Dulac, C. (May 11, 1999). "TRP2: A candidate transduction channel for mammalian pheromone sensory signaling". Proceedings of the National Academy of Sciences. 96 (10): 5791–5796. Bibcode:1999PNAS...96.5791L. doi:10.1073/pnas.96.10.5791. ISSN 0027-8424. PMC 21939. PMID 10318963.
- Belluscio, Leonardo; Koentges, Georgy; Axel, Richard; Dulac, Catherine (1999). "A Map of Pheromone Receptor Activation in the Mammalian Brain". Cell. 97 (2). Elsevier BV: 209–220. doi:10.1016/s0092-8674(00)80731-x. ISSN 0092-8674. PMID 10219242. S2CID 18385498.
- Dulac, Catherine; Axel, Richard (1995). "A novel family of genes encoding putative pheromone receptors in mammals". Cell. 83 (2). Elsevier BV: 195–206. doi:10.1016/0092-8674(95)90161-2. ISSN 0092-8674. PMID 7585937. S2CID 18784638.
Other
- Dulac, Catherine (2005). "Sex and the Single Splice". Cell. 121 (5). Elsevier BV: 664–666. doi:10.1016/j.cell.2005.05.017. ISSN 0092-8674. PMID 15935752. S2CID 15137565.
- "Sensory systems". Current Opinion in Neurobiology. 14 (4). Elsevier BV: 403–406. 2004. doi:10.1016/j.conb.2004.07.010. ISSN 0959-4388. S2CID 54341126.
- Dulac, Catherine; Torello, A. Thomas (2003). "Molecular detection of pheromone signals in mammals: from genes to behaviour". Nature Reviews Neuroscience. 4 (7). Springer Science and Business Media LLC: 551–562. doi:10.1038/nrn1140. ISSN 1471-003X. PMID 12838330. S2CID 11120696.
- Dulac, Catherine (2000). "The Physiology of Taste, Vintage 2000". Cell. 100 (6). Elsevier BV: 607–610. doi:10.1016/s0092-8674(00)80697-2. ISSN 0092-8674. PMID 10761926. S2CID 7721853.
Awards and honors
- 1998 Searle Scholar[21]
- 2004 Member, American Academy of Arts and Sciences[21][22]
- 2006 Richard Lounsbery Award[21]
- 2007 Member, French Academy of Sciences[21]
- 2010 Perl-UNC Prize
- 2015 Pradel Research Award by the National Academy of Sciences[21]
- 2017 Scolnick Prize by the McGovern Institute
- 2018 Karl Spencer Lashley Award
- 2019 Ralph W. Gerard Prize in Neuroscience[23]
- 2021 Breakthrough Prize in Life Sciences[24]
She was elected a Member of the American Philosophical Society in 2019.[25]
References
- ^ a b c d e f g h i "Catherine Dulac" (PDF) (in French). French Academy of Sciences. Archived from the original (PDF) on February 6, 2024. Retrieved February 6, 2024.
- ^ a b "CATHERINE DULAC'S PHENOMENAL PHEROMONE FASCINATION". Department of Molecular and Cellular Biology, Harvard University. August 6, 2007. Archived from the original on February 7, 2024. Retrieved February 7, 2024.
- ^ "Catherine Dulac". Harvard Magazine. No. September-October 2005. 2005. Archived from the original on February 8, 2024. Retrieved February 8, 2024.
- ^ "Les Membres de l'Académie des sciences élus en 2007" (PDF) (in French). French Academy of Sciences. Archived from the original (PDF) on February 6, 2024. Retrieved February 6, 2024.
- ^ "Harvard scientist Catherine Dulac awarded for work on parenting instinct". Radio France Internationale. September 14, 2020. Archived from the original on February 8, 2024. Retrieved February 8, 2024.
- ^ a b "Etude de la differenciation des cellules gliales dans le systeme nerveux peripherique". Theses.fr. Archived from the original on February 8, 2024. Retrieved February 8, 2024.
- ^ "Dulac, Sampson, and Sharpe honored with highest distinction for a faculty member". The Harvard Gazette. November 28, 2022. Archived from the original on February 7, 2024. Retrieved February 7, 2024.
- ^ "Catherine Dulac". Department of Molecular and Cellular Biology, Harvard University. Archived from the original on February 6, 2024. Retrieved February 6, 2024.
- ^ Li, Katelyn X. (April 19, 2018). "Four Harvard Faculty Awarded Arts and Sciences Professorships". The Harvard Crimson. Archived from the original on February 14, 2024. Retrieved February 14, 2024.
- ^ a b Gitschier, Jane (2011). "Vive La Différence: An Interview with Catherine Dulac". PLOS Genetics. 7 (6): e1002140. doi:10.1371/journal.pgen.1002140. Archived from the original on February 15, 2024. Retrieved February 15, 2024.
{{cite journal}}
: CS1 maint: unflagged free DOI (link) - ^ "Entretien avec la neurobiologiste Catherine Dulac" (in French). École Normale Supérieure. Archived from the original on February 14, 2024. Retrieved February 14, 2024.
- ^ Le Douarin, Nicole (2005). "The Nogent Institute - 50 Years of Embryology". The International Journal of Developmental Biology. 49 (2–3): 85–103. doi:10.1387/ijdb.041952nl. PMID 15906221. Archived from the original on February 15, 2024. Retrieved February 15, 2024.
- ^ "Molecular and neural architecture of circuits underlying social behavior in the mouse". Simons Foundation. Archived from the original on February 15, 2024. Retrieved February 15, 2024.
- ^ Jennings, Charles. "McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac". MIT News. Archived from the original on February 9, 2024. Retrieved February 9, 2024.
- ^ Simon, Clea (May 23, 2019). "Giving to the next generation". The Harvard Gazette. Retrieved February 18, 2024.
{{cite news}}
:|archive-date=
requires|archive-url=
(help) - ^ "Three New University Professors". Harvard Magazine. November 30, 2022. Archived from the original on February 18, 2024. Retrieved February 18, 2024.
- ^ Kim, Ariel H.; Xu, Meimei (November 30, 2022). "Three Harvard Scholars Named University Professors, Highest Faculty Distinction". The Harvard Crimson. Archived from the original on February 18, 2024. Retrieved February 18, 2024.
- ^ Gitschier, J. (2011). "Vive La Différence: An Interview with Catherine Dulac". PLOS Genetics. 7 (6): e1002140. doi:10.1371/journal.pgen.1002140. PMC 3121755. PMID 21731502.
- ^ "McGovern Institute awards 2017 Scolnick Prize to Catherine Dulac". MIT News. Retrieved February 3, 2018.
- ^ "Catherine Dulac". Harvard University. Archived from the original on June 15, 2011. Retrieved June 15, 2011.
- ^ a b c d e Cite error: The named reference
CV
was invoked but never defined (see the help page). - ^ Hastings, J. W. (May 12, 2004) "Catherine Dulac Elected to Membership in the American Academy of Arts and Sciences" Archived 2016-11-15 at the Wayback Machine, Harvard University MCB News.
- ^ "Dulac Receives Award from Society for Neuroscience". Harvard University – Department of Molecular & Cellular Biology. October 19, 2019. Retrieved September 10, 2020.
- ^ Knapp, Alex. "2021 Breakthrough Prize Winners Announced: Researcher Who Developed Protein Design Technology Awarded $3 Million". Forbes. Retrieved September 10, 2020.
- ^ "Catherine Dulac Elected to American Philosophical Society". Harvard University – Department of Molecular & Cellular Biology. June 13, 2019. Retrieved September 10, 2020.
External links
- Research Summary & Profile, Harvard University
- HHMI profile Archived 2013-05-11 at the Wayback Machine
- "Pheromones Control Gender Recognition in Mice", January 31, 2002 (HHMI Research News)
- "Harvard Portrait: Catherine Dulac",
- "Making the Paper: Catherine Dulac", Nature, v.448 (August 30, 2007).
- Catherine Dulac Seminars
Category:1963 births Category:Living people Category:21st-century American biologists Category:Howard Hughes Medical Investigators Category:University of Paris alumni Category:Columbia University people Category:Harvard University faculty Category:Fellows of the American Academy of Arts and Sciences Category:Members of the French Academy of Sciences Category:American women biologists Category:Members of the American Philosophical Society Category:Members of the United States National Academy of Sciences Category:Richard-Lounsbery Award laureates Category:American neuroscientists Category:American women neuroscientists Category:American women academics Category:French emigrants to the United States Category:21st-century American women scientists