Talk:Benign familial neonatal seizures

Untitled

There is a discrepancy: - Paragraph 1: "Lifetime susceptibility to seizures is increased" - Paragraph 3: "People with BFNE are not more likely to develop epileptic seizures later in life" — Preceding unsigned comment added by 130.132.173.166 (talk) 04:18, 10 June 2014 (UTC)

Wiki Education assignment: WikiMed UTSW

This article was the subject of a Wiki Education Foundation-supported course assignment, between 21 November 2023 and 15 December 2023. Further details are available on the course page. Student editor(s): Yalayli (article contribs).

— Assignment last updated by Yalayli (talk) 00:27, 22 November 2023 (UTC)

In text citations missing:

Paragraph 1

The entire first paragraph is without citations.

Signs and symptoms

"The only sign of BFNE are seizures, generally tonic-clonic, which occur within the first week of life. Seizures often begin as apnea, cyanosis, and hypertonia and last less than one minute."

Pathophysiology

Section on BFNC1 has several facts that are not cited.

Management

None

Workplan

Monday 11-20 • Reviewed Wikiproject Medicine’s website • completed all required Wiki Ed training modules by day 2 • begun thinking about what article I want to work on this month

Monday 11-27 • Finish my work plan • Start finalizing literature sources to incorporate into the article • Finish personal literature review and study of topic

Friday 12/1 • Review article to make sure that everything is relevant to the topic/ there are no distractions, edit accordingly • Check article for any bias or under/overrepresented information, edit accordingly • Incorporate up to date information where it is needed

Wed 12/6

• Assess quality of citations and that they align with their use, edit accordingly • Edit article to limit medical jargon. Check citation links for functionality. • Edit article to include more information on signs/symptoms

Monday 12-11 • Incorporate information on co-morbidities and long-term management • Edit article to provide more information on history • Imbed links to other relevant wiki pages

Friday 12-15 • Incorporate information on first cases documented and famous cases documented. Incorporate more information on pathophysiology outside of genetic mutations • Review entire article to ensure citations are valid, there is no bias, and all information is relevant — Preceding unsigned comment added by 2603:8080:6CF0:B370:BD78:4508:8C10:265D (talk) 18:52, 27 November 2023 (UTC)

Wiki Education Peer Review

Overall I really like this article. It goes into a rare genetic illness and does a good job explaining what we know and what we don’t know. The lead paragraph succinctly goes over all the things I would want to know about this illness including etiology, symptoms, prognosis.

One thing I would work on is the pathophysiology section. As you mentioned in class it’s hard to make the basic science readable for lay audiences. One helpful thing could be to explain what M current/whole cell current is and describe how it relates to what you say at the end of that paragraph about the mutations leading to hyperexcitability, and why that leads to seizures. I think whole cell current is used later to describe the other kinds of mutations, and it seems important to know what it is in this section, even though it is linked to.

One thing is I’m not sure what BFNC1/2/3 are. After reading this article, they seem to be classes of the disease, but I don’t think it’s stated what the acronym stands for. In the beginning of the pathophysiology section the sub heading is BFNC1, but then it starts talking about the KCNQ2 gene, and I didn’t understand the relationship at first.

One last thing is I think for some of these rare diseases it’s cool to see a “1 in 1,000,000” live births or some ratio to give a sense of how common it is. Otherwise I like the article and think it is flows/reads well! -Ferozemide (talk) 02:08, 11 December 2023 (UTC)