Sikhanyiso is a South African given name. Notable people with the name include:
- Sikhanyiso Dlamini (born 1987), eldest daughter of King Mswati III of Swaziland
- Sikhanyiso Ndlovu (1937–2015), Zimbabwean politician and a former Minister of Information and Publicity
This page or section lists people that share the same given name.
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