McNichols is a surname. Notable people with the surname include:
- Jeremy McNichols (born 1995), American football player
- John J. McNichols (1927–2020), American politician and lawyer
- Raymond Clyne McNichols (1914–1985), United States federal judge
- Robert James McNichols (1922–1993), United States federal judge
- Stephen L.R. McNichols (1914–1997), Colorado's 35th Governor from 1957 to 1963
- William Hart McNichols (born 1949), American Roman Catholic priest and artist
See also
edit- McNichols Sports Arena ("Big Mac"), indoor arena in Denver, Colorado, USA