IPO11

Importin-11 is a protein that in humans is encoded by the IPO11 gene.

IPO11
Identifiers
Aliases	IPO11, RanBP11, importin 11
External IDs	OMIM: 610889; MGI: 2442377; HomoloGene: 7089; GeneCards: IPO11; OMA:IPO11 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) Band 5q12.1 Start 62,403,972 bp End 62,628,582 bp
Gene location (Mouse) Chr. Chromosome 13 (mouse) Band 13|13 D1- D2.1 Start 106,930,947 bp End 107,073,466 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad testicle epithelium of colon bronchial epithelial cell ventricular zone right testis left testis sperm Achilles tendon olfactory zone of nasal mucosa Top expressed in tail of embryo genital tubercle blood primitive streak somite spermatocyte ventricular zone utricle epiblast cumulus cell More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding nuclear import signal receptor activity Cellular component cytoplasm fibrillar center nucleus nuclear envelope cytosol Biological process protein transport intracellular protein transport ribosomal protein import into nucleus protein import into nucleus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51194 76582 Ensembl ENSG00000086200 ENSMUSG00000042590 UniProt Q9UI26 Q8K2V6 RefSeq (mRNA) NM_016338 NM_001134779 NM_029665 NM_001360897 NM_175202 RefSeq (protein) NP_001128251 NP_057422 NP_083941 NP_001347826 Location (UCSC) Chr 5: 62.4 – 62.63 Mb Chr 13: 106.93 – 107.07 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Plafker SM, Macara IG (2000). "Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2". EMBO J. 19 (20): 5502–13. doi:10.1093/emboj/19.20.5502. PMC 314000. PMID 11032817.
• Plafker SM, Macara IG (2002). "Ribosomal protein L12 uses a distinct nuclear import pathway mediated by importin 11". Mol. Cell. Biol. 22 (4): 1266–75. doi:10.1128/MCB.22.4.1266-1275.2002. PMC 134630. PMID 11809816.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wang W, Yang Y, Li L, Shi Y (2003). "Synleurin, a novel leucine-rich repeat protein that increases the intensity of pleiotropic cytokine responses". Biochem. Biophys. Res. Commun. 305 (4): 981–8. doi:10.1016/S0006-291X(03)00876-3. PMID 12767927.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.