Guvacine

Guvacine
Names
	Preferred IUPAC name 1,2,5,6-Tetrahydropyridine-3-carboxylic acid
Identifiers
CAS Number	498-96-4;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL76768;
ChemSpider	3412;
IUPHAR/BPS	4691;
KEGG	C10149;
PubChem CID	3532;
UNII	41538P325K ;
CompTox Dashboard (EPA)	DTXSID50871702 ;
	InChI InChI=1S/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9) Key: QTDZOWFRBNTPQR-UHFFFAOYSA-N; InChI=1/C6H9NO2/c8-6(9)5-2-1-3-7-4-5/h2,7H,1,3-4H2,(H,8,9) Key: QTDZOWFRBNTPQR-UHFFFAOYAX;
	SMILES C1CNCC(=C1)C(=O)O;
Properties
Chemical formula	C6H9NO2
Molar mass	127.143 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Guvacine is an hydrogenated pyridine alkaloid found in areca nuts.^[1] It is the N-demethylated derivative of arecaidine and the product of ester hydrolysis of guvacoline, both of which are also found in areca nuts as well. It is also an inhibitor of gamma-aminobutyric acid uptake. Lime is said to hydrolyse guvacoline to guvacine.^[2]

References