Dimefox

Dimefox
Names
	IUPAC name N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine
	Other names TL-792; T-2002
Identifiers
CAS Number	115-26-4 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:82119 ;
ChemSpider	7966 ;
ECHA InfoCard	100.003.706
EC Number	204-076-8;
KEGG	C18980 ;
PubChem CID	8264;
UNII	N8RU9F1IQD ;
CompTox Dashboard (EPA)	DTXSID8041870 ;
	InChI InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 Key: PGJBQBDNXAZHBP-UHFFFAOYSA-N ; InChI=1/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 Key: PGJBQBDNXAZHBP-UHFFFAOYAM;
	SMILES CN(C)P(=O)(N(C)C)F;
Properties
Chemical formula	C4H12FN2OP
Molar mass	154.125 g·mol−1
Appearance	colourless liquid
Density	1.11 g·mL–1
Solubility in water	14.8 g·L–1
Vapor pressure	14663 mPa
Henry's law; constant (kH)	2.28·10–8 atm·m3·mol–1
Pharmacology
Routes of; administration	inhalation and dermal contact
Legal status	UK: Banned; US: Banned;
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Highly Toxic
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300, H310
Precautionary statements	P262, P264, P270, P280, P301 P310, P302 P350, P310, P321, P322, P330, P361, P363, P405, P501
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	2 mg/kg (oral, mice); 1 mg/kg (oral, rats); 3 mg/kg (intravenous, rabbits)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Dimefox, also known as TL-792 or T-2002, is a highly toxic organophosphate insecticide. In its pure form it is a colourless liquid with a fishy odour.^[3] Dimefox was first produced in 1940 by the group of Gerhard Schrader in Germany. It was historically used as a pesticide, but has been deemed obsolete or discontinued for use by the World Health Organization due to being an inhibitor of acetylcholinesterase.^{[citation needed]} It is not guaranteed that all commercial use of this compound ceased, but in most countries^[which?] it is no longer registered for use as a pesticide.^[4] It is considered an extremely hazardous substance as defined by the United States Emergency Planning and Community Right-to-Know Act.

References

^ ^a ^b ^c ^d ^e Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
^ "Dimefox".
^ "IUPAC FOOTPRINT Pesticides Properties Database". Archived from the original on 2011-07-22. Retrieved 2011-04-06.
^ the WHO recommended classification of pesticides by hazard and guidelines to classification 2009, [1]

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Names


IUPAC name N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine
Other names TL-792^[1] T-2002^[1]
Identifiers
CAS Number	115-26-4^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:82119^Y
ChemSpider	7966^Y
ECHA InfoCard	100.003.706
EC Number	204-076-8
KEGG	C18980^Y
PubChem CID	8264
UNII	N8RU9F1IQD^Y
CompTox Dashboard (EPA)	DTXSID8041870
InChI InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3^N Key: PGJBQBDNXAZHBP-UHFFFAOYSA-N^N InChI=1/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 Key: PGJBQBDNXAZHBP-UHFFFAOYAM
SMILES CN(C)P(=O)(N(C)C)F
Properties
Chemical formula	C₄H₁₂FN₂OP
Molar mass	154.125 g·mol⁻¹
Appearance	colourless liquid
Density	1.11 g·mL^–1
Solubility in water	14.8 g·L^–1
Vapor pressure	14663 mPa
Henry's law constant (k_H)	2.28·10^–8 atm·m³·mol^–1^[2]
Pharmacology
Routes of administration	inhalation and dermal contact
Legal status	UK: Banned US: Banned
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Highly Toxic
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H300, H310
Precautionary statements	P262, P264, P270, P280, P301 P310, P302 P350, P310, P321, P322, P330, P361, P363, P405, P501
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	2 mg/kg (oral, mice)^[1] 1 mg/kg (oral, rats)^[1] 3 mg/kg (intravenous, rabbits)^[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references