DDX52

Probable ATP-dependent RNA helicase DDX52 is an enzyme that in humans is encoded by the DDX52 gene.

DDX52
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3DKP
Identifiers
Aliases	DDX52, HUSSY19, ROK1, DEAD-box helicase 52, DExD-box helicase 52
External IDs	OMIM: 612500; MGI: 1925644; HomoloGene: 5093; GeneCards: DDX52; OMA:DDX52 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17q12 Start 37,609,739 bp End 37,643,446 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 C Start 83,832,888 bp End 83,853,914 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve endometrium testicle ganglionic eminence islet of Langerhans ventricular zone rectum gonad smooth muscle tissue Achilles tendon Top expressed in genital tubercle spermatocyte tail of embryo ventricular zone primitive streak morula epiblast otic vesicle endothelial cell of lymphatic vessel medullary collecting duct More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding hydrolase activity ATP binding helicase activity nucleic acid binding RNA binding Cellular component membrane nucleoplasm nucleus nucleolus cytoplasm Biological process RNA secondary structure unwinding rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11056 78394 Ensembl ENSG00000277863 ENSG00000278053 ENSMUSG00000020677 UniProt Q9Y2R4 Q8K301 RefSeq (mRNA) NM_001291476 NM_007010 NM_152300 NM_030096 RefSeq (protein) NP_001278405 NP_008941 NP_084372 Location (UCSC) Chr 17: 37.61 – 37.64 Mb Chr 11: 83.83 – 83.85 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.