Clenoliximab (INN[1]) is a monoclonal antibody against CD4. It acts as an immunomodulator and has been investigated for the treatment of rheumatoid arthritis.[2] The drug is a chimeric antibody from Macaca irus and Homo sapiens.[1]
| Monoclonal antibody | |
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| Type | Whole antibody |
| Source | Chimeric (primate/human) |
| Target | CD4 |
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References
edit- ^ a b World Health Organization (1997). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 77" (PDF). WHO Drug Information. 11 (2): 89. Archived from the original (PDF) on June 27, 2004.
- ^ Hepburn TW, Totoritis MC, Davis CB (January 2003). "Antibody-mediated stripping of CD4 from lymphocyte cell surface in patients with rheumatoid arthritis". Rheumatology. 42 (1): 54–61. doi:10.1093/rheumatology/keg030. PMID 12509613.
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