Steen Knudsen

Featured on the inside front cover of issue 10 of #NanoscaleAdvances! 'Embedding plasmonic nanoparticles in soft crystals: an approach exploiting CTAB–I structures' by Anshu Pandey et al. Read the full article here: https://lnkd.in/eB6BPTbi

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Two recent papers -- by Fojo and Olivier -- explained why Sotorasib, a KRAS G12C inhibitor, became a regulatory setback for NSCLC? They wrote: Sotorasib was approved on the basis of a single-arm, uncontrolled phase 1–2 study (CodeBreaK 100) that reported an objective response rate (ORR) of 37% and a 11·1 month median duration of response. By contrast, other molecular therapies for NSCLC have higher ORRs; osimertinib targets EGFR-mutated NSCLC and has an ORR of 90% and alectinib targets ALK-mutated NSCLC and has reported an ORR of 82·9%.

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Catch a recap of a recent #ISCT2024 roundtable in #Vancouver moderated by Dalip Sethi, PhD, MBA - "Current State and Future Directions of #ProcessAnalyticalTechnologies in the CGT Space." #CellGeneTherapies #CellTherapy #GeneTherapy #PAT ISCT, International Society for Cell & Gene Therapy

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This review has highlighted the mechanisms of #nanoparticle synthesis, functionalization and attachment of #biomolecules for use in the delivery of #therapeutic agents for #tissue regeneration. Nano Biomed. Eng. https://lnkd.in/gC-QkJN4

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Understand the implications of ILD toxicity monitoring in Antibody Drug Conjugate (#ADC\) trials and how to meet worldwide #regulatory expectations in this on-demand webinar. https://lnkd.in/gsFnCN8p #MedicalImaging #Oncology #ChooseCalyx

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Dear Researchers/Professors We are editing topic-specific manuscript collection for ‘Frontiers in Pharmacology and Frontiers in Oncology, journals, specialty section, ‘Pharmacology of Anti-Cancer Drugs’ Title of Topic: Plant Bioactive as Modulators of Oncogenic Signalling Pathways in Cervical Cancer  Submissions must be related to cervical cancer, including, but not limited to, the following themes are welcome: • The mechanisms of cervical cancer's abnormal signal transduction pathways and their effects on carcinogenesis, apoptosis, and metastasis. • Role of plant phytochemicals in the cell signalling modulations in cervical cancer. • Therapeutic potential of plant phytochemicals by targeting multiple oncogenic signalling pathways in cervical cancer • Natural products as EMT modulators used in cervical cancer • Potential adjuvant therapies of plant products with chemotherapeutic drugs in cervical cancer therapy. • Plant products nanoformulations as cell signalling modulators in cervical cancer." Interested authors can send details: Name, affiliation, email ID and tentative title of the study at [email protected] Topic Editors, Dr. Fahad Khan, Dr. Arif Hussain, Dr. Pratibha Pandey https://lnkd.in/gF-5TfE8 

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