CrystalsFirst

🎉 Our "Magnet for the Needle" paper that has been featured on the cover of the Journal of Medicinal Chemistry! Screening campaigns for hit finding are often paraphrased as searching for the “needle in the haystack”. The newly proposed “crystal structure first” approach mines active compounds from billions of purchasable chemical space, just like a strong magnet pulls from huge haystacks. The effectiveness of "crystal structure first" in a nut shell:  ✅ fragment-to-hit success 40 % ✅ timeframe only 9 weeks  ✅ from mM to low µM and even nM in one cycle Check out the publication: https://lnkd.in/eAkRJANK #crystallography #medicinalchemistry #structuralbiology #FBDD #SBDD #drugdiscovery

Another 💎 is joining the growing Machine Learning team in Hamburg. Welcome Shehryar!

🌟 Celebrating Five Years of Stellar Growth at CrystalsFirst! 🌟 We are proud to announce that CrystalsFirst has achieved remarkable growth for the fifth year in a row. This milestone is a testament to the dedication and excellence of our team and our commitment to advancing drug discovery and structural biology. Our highlights include enabling over 40 drug targets and establishing ourselves as a trusted partner in the field of drug discovery and structural biology. To celebrate our success, our team gathered in Lisbon for 👥 Engaging workshops to foster collaboration and innovation 🏄♂️ Surfing sessions on the stunning Portuguese waves 🌞 Relaxing beach days to strengthen our team bonds 🍴 Enjoying the delightful local cuisine together At CrystalsFirst, our company culture resonates deeply with the biotech community. We prioritize innovation, collaboration, and pursuit of excellence. Our team’s passion and commitment drive us to push boundaries and deliver impactful solutions for our partners. Here’s to many more years of growth and success!

Another 💎 is joining the growing structural biology team in Hamburg. Welcome Josephine!

💎 We are very excited to welcome another Crystal in our company! Stella Marazidou is part of our growing protein production team in Göttingen. 

💎 Our approach to scale the design of therapeutics drew attention of Dr. Robert Habeck , Federal Minister for Economic Affairs and Climate Action, during his visit at the Life Science Factory. Pictures: ©Marco Bühl

💎 We are very excited to welcome another Crystal in our company! Henry Gieseler is joining the growing structural biology team in Hamburg.

Meet our CEO Serghei Glinca at the 7th  Sachs Associates' Annual European Life Sciences CEO Forum taking place in Zurich from 28th to 29th of February.    The event is an opportunity to connect and discuss: - How SmartSoak® screening has enabled drug discovery for challenging targets - Advantages of structural data for generative AI  - Partnering opportunities

💎 We are very excited to welcome another Crystal in our company! Sabrina Stäb is joining the growing structural biology team in Hamburg.

💎 𝗠𝗘𝗘𝗧 𝗢𝗨𝗥 𝗖𝗥𝗬𝗦𝗧𝗔𝗟𝗦 Marieke Enders is dedicated to optimizing processes to enable the large-scale production of proteins for X-ray crystallography. While each project presents unique demands and obstacles, Marieke consistently devises innovative solutions that guarantee the successful production of high-quality proteins. “In protein production, we are dedicated to provide high-quality material for crystallography. I enjoy the challenge of developing efficient purification strategies for our diverse targets.” - Marieke Enders #proteinsciences #proteinpurification #crystallography #FBDD #medicinalchemistry #structuralbiology #drugdiscovery