SLAMF1

SLAMF1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1M27, 1KA7, 1I3Z, 1D4T, 1D4W, 1KA6
Dynodwyr
Cyfenwau	SLAMF1, CD150, CDw150, SLAM, signaling lymphocytic activation molecule family member 1
Dynodwyr allanol	OMIM: 603492 HomoloGene: 48162 GeneCards: SLAMF1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• GO:0003823, GO:0051635 antigen binding; • virus receptor activity; • GO:0001948, GO:0016582 protein binding; • transmembrane signaling receptor activity; • identical protein binding; • signaling receptor activity;
Cydrannau o'r gell	• integral component of membrane; • bilen; • Cellbilen; • extracellular region; • cell surface; • phagocytic vesicle; • extracellular exosome; • external side of plasma membrane;
Prosesau biolegol	• adaptive immune response; • immune system process; • natural killer cell proliferation; • T-helper 1 cell cytokine production; • negative regulation of interleukin-6 production; • positive regulation of JNK cascade; • cell adhesion; • negative regulation of CD40 signaling pathway; • negative regulation of T cell cytokine production; • myeloid dendritic cell activation involved in immune response; • regulation of vesicle fusion; • positive regulation of cell population proliferation; • positive regulation of ERK1 and ERK2 cascade; • ffagocytosis; • lymphocyte activation; • viral entry into host cell; • negative regulation of tumor necrosis factor production; • innate immune response; • GO:0048552 regulation of catalytic activity; • GO:0022415 viral process; • positive regulation of activated T cell proliferation; • negative regulation of interleukin-12 production; • natural killer cell differentiation; • GO:0072468 signal transduction; • leukocyte chemotaxis involved in inflammatory response; • positive regulation of macrophage chemotaxis; • positive regulation of dendritic cell chemotaxis;
	Sources:Amigo / QuickGO
Orthologau
	6504
	n/a
	ENSG00000117090
	n/a
	Q13291
	n/a
	NM_003037; NM_001330754
	n/a
	NP_001317683; NP_003028
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SLAMF1 yw SLAMF1 a elwir hefyd yn Signaling lymphocytic activation molecule family member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SLAMF1.

SLAM
CD150
CDw150

Llyfryddiaeth

"Analysis of expression and function of the co-stimulatory receptor SLAMF1 in immune cells from patients with systemic lupus erythematosus (SLE). ". Lupus. 2015. PMID 25920347.
"Upstream open reading frames regulate translation of the long isoform of SLAMF1 mRNA that encodes costimulatory receptor CD150. ". Biochemistry (Mosc). 2014. PMID 25716736.
"The Measles Virus Receptor SLAMF1 Can Mediate Particle Endocytosis. ". J Virol. 2017. PMID 28100610.
"Differential expression of CD150/SLAMF1 in normal and malignant B cells on the different stages of maturation. ". Exp Oncol. 2016. PMID 27356578.
"SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response.". J Clin Invest. 2016. PMID 26619119.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] SLAMF1 - Cronfa NCBI

[1]

[2]