PPP1R9A

PPP1R9A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WF8
Dynodwyr
Cyfenwau	PPP1R9A, NRB1, NRBI, Neurabin-I, protein phosphatase 1 regulatory subunit 9A
Dynodwyr allanol	OMIM: 602468 HomoloGene: 14247 GeneCards: PPP1R9A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • protein domain specific binding • protein phosphatase 1 binding • GO:0001948, GO:0016582 protein binding • GTPase binding • actin binding • actin filament binding • protein C-terminus binding • protein kinase binding • transmembrane transporter binding • GO:0032403 protein-containing complex binding Cydrannau o'r gell • dendritic spine neck • cytosol • filopodium • growth cone • neuromuscular junction • dendritic spine • synapse • growth cone lamellipodium • cell junction • soma • cortical actin cytoskeleton • neuron projection • Cytosgerbwd • lamellipodium • cytoplasm • GO:0097483, GO:0097481 postsynaptic density • actin cytoskeleton • dendrite • postsynaptic actin cytoskeleton • glutamatergic synapse Prosesau biolegol • regulation of filopodium assembly • cell differentiation • regulation of synapse structural plasticity • regulation of synapse assembly • GO:0010260 heneiddio • cellular response to toxic substance • neuron development • positive regulation of dendritic spine development • nervous system development • multicellular organism development • regulation of actin filament polymerization • excitatory postsynaptic potential • negative regulation of long-term synaptic potentiation • negative regulation of spontaneous neurotransmitter secretion • positive regulation of long-term synaptic depression • positive regulation of neuron projection development • negative regulation of stress fiber assembly • regulation of dendritic spine morphogenesis • positive regulation of protein kinase activity • actin filament organization • calcium-mediated signaling • neuron projection development • modulation of chemical synaptic transmission • postsynaptic actin cytoskeleton organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55607	n/a
Ensembl	ENSG00000158528	n/a
UniProt	Q9ULJ8	n/a
RefSeq (mRNA)	NM_001166160 NM_001166161 NM_001166162 NM_001166163 NM_017650	n/a
RefSeq (protein)	NP_001159632 NP_001159633 NP_001159634 NP_001159635 NP_060120 NP_001159635.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPP1R9A yw PPP1R9A a elwir hefyd yn PPP1R9A protein a Neurabin-1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPP1R9A.

• NRB1
• NRBI
• Neurabin-I

Llyfryddiaeth

• "Structural basis for protein phosphatase 1 regulation and specificity. ". FEBS J. 2013. PMID 22284538.
• "Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formation. ". J Cell Biol. 1997. PMID 9362513.
• "Genomic imprinting of PPP1R9A encoding neurabin I in skeletal muscle and extra-embryonic tissues. ". J Med Genet. 2004. PMID 15286155.
• "Altered prefrontal cortical MARCKS and PPP1R9A mRNA expression in schizophrenia and bipolar disorder. ". Schizophr Res. 2015. PMID 25757715.
• "Integrative genomic and transcriptomic analysis identified candidate genes implicated in the pathogenesis of hepatosplenic T-cell lymphoma.". PLoS One. 2014. PMID 25057852.