MAPRE3

MAPRE3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WYO, 3CO1, 3JAK, 3JAL, 3JAR, 3TQ7
Dynodwyr
Cyfenwau	MAPRE3, EB3, EBF3, EBF3-S, RP3, microtubule associated protein RP/EB family member 3
Dynodwyr allanol	OMIM: 605788 HomoloGene: 56565 GeneCards: MAPRE3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • microtubule binding • GO:0001948, GO:0016582 protein binding • identical protein binding • protein C-terminus binding • protein kinase binding • microtubule plus-end binding Cydrannau o'r gell • microtubule cytoskeleton • microtubule plus-end • perinuclear region of cytoplasm • cytoplasmic microtubule • midbody • microtubule • Cytosgerbwd • cytoplasm • microtubule organizing center • spindle midzone • mitotic spindle astral microtubule end Prosesau biolegol • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • cell cycle • positive regulation of microtubule plus-end binding • positive regulation of cyclin-dependent protein serine/threonine kinase activity • Cellraniad • GO:0034613 protein localization • regulation of microtubule polymerization or depolymerization • protein localization to microtubule • positive regulation of protein kinase activity • spindle assembly • protein localization to microtubule plus-end Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	22924	n/a
Ensembl	ENSG00000084764	n/a
UniProt	Q9UPY8	n/a
RefSeq (mRNA)	NM_001303050 NM_012326	n/a
RefSeq (protein)	NP_001289979 NP_036458	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAPRE3 yw MAPRE3 a elwir hefyd yn Microtubule associated protein RP/EB family member 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAPRE3.

• EB3
• RP3
• EBF3
• EBF3-S

Llyfryddiaeth

• "End binding proteins are obligatory dimers. ". PLoS One. 2013. PMID 24040250.
• "Aurora B spatially regulates EB3 phosphorylation to coordinate daughter cell adhesion with cytokinesis. ". J Cell Biol. 2013. PMID 23712260.
• "The drebrin/EB3 pathway drives invasive activity in prostate cancer. ". Oncogene. 2017. PMID 28319065.
• "Frameshift mutation of MAPRE3, a microtubule-related gene, in gastric and colorectal cancers with microsatellite instability. ". Pathology. 2010. PMID 20632835.
• "EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.". J Cell Biol. 2017. PMID 28814570.