MAFG

MAFG
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1K1V, 3A5T
Dynodwyr
Cyfenwau	MAFG, hMAF, MAF bZIP transcription factor G
Dynodwyr allanol	OMIM: 602020 HomoloGene: 81816 GeneCards: MAFG
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • sequence-specific DNA binding Cydrannau o'r gell • nucleoplasm • cnewyllyn cell Prosesau biolegol • regulation of epidermal cell differentiation • GO:1901313 positive regulation of gene expression • adult behavior • blood coagulation • in utero embryonic development • regulation of cell population proliferation • regulation of cellular pH • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • transcription by RNA polymerase II • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4097	n/a
Ensembl	ENSG00000197063	n/a
UniProt	O15525	n/a
RefSeq (mRNA)	NM_002359 NM_032711	n/a
RefSeq (protein)	NP_002350 NP_116100	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAFG yw MAFG a elwir hefyd yn MAF bZIP transcription factor G (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAFG.

• hMAF

Llyfryddiaeth

• "Picosecond-hetero-FRET microscopy to probe protein-protein interactions in live cells. ". Biophys J. 2002. PMID 12496124.
• "Molecular characterization and localization of the human MAFG gene. ". Genomics. 1997. PMID 9286713.
• "hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2. ". J Biol Chem. 1997. PMID 9195958.
• "The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype. ". Mol Cell. 2014. PMID 25219500.
• "Small MAF genes variants and chronic myeloid leukemia.". Eur J Haematol. 2014. PMID 24118457.