LAMTOR5

LAMTOR5
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3MS6, 3MSH
Dynodwyr
Cyfenwau	LAMTOR5, HBXIP, XIP, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Dynodwyr allanol	OMIM: 608521 HomoloGene: 4668 GeneCards: LAMTOR5
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• guanyl-nucleotide exchange factor activity; • GO:0001948, GO:0016582 protein binding; • GO:0032947 molecular adaptor activity;
Cydrannau o'r gell	• cytoplasm; • cytosol; • Ragulator complex; • lysosomal membrane; • lysosome;
Prosesau biolegol	• regulation of cell size; • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; • viral genome replication; • response to virus; • negative regulation of apoptotic process; • protein localization to lysosome; • cellular response to amino acid stimulus; • positive regulation of TOR signaling; • regulation of macroautophagy; • positive regulation of TORC1 signaling;
	Sources:Amigo / QuickGO
Orthologau
	10542
	n/a
	ENSG00000134248
	n/a
	O43504
	n/a
	NM_006402; NM_001382293
	n/a
	NP_006393; NP_001369222; NP_006393.2
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn LAMTOR5 yw LAMTOR5 a elwir hefyd yn Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 a Hepatitis B virus x interacting protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p13.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn LAMTOR5.

XIP
HBXIP

Llyfryddiaeth

"Hepatitis B X-interacting protein promotes cisplatin resistance and regulates CD147 via Sp1 in ovarian cancer. ". Exp Biol Med (Maywood). 2017. PMID 28056551.
"Suppression of HBXIP Reduces Cell Proliferation, Migration and Invasion In Vitro, and Tumorigenesis In Vivo in Human Urothelial Carcinoma of the Bladder. ". Cancer Biother Radiopharm. 2016. PMID 27831760.
"HBXIP suppression reduces cell proliferation and migration and its overexpression predicts poor prognosis in non-small-cell lung cancer. ". Tumour Biol. 2017. PMID 28718367.
"HBXIP overexpression is correlated with the clinical features and survival outcome of ovarian cancer. ". J Ovarian Res. 2017. PMID 28388957.
"HBXIP over expression as an independent biomarker for cervical cancer.". Exp Mol Pathol. 2017. PMID 28093193.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] LAMTOR5 - Cronfa NCBI

[1]

[2]