IL2RG

IL2RG
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2B5I, 2ERJ, 3BPL, 3QAZ, 3QB7, 4GS7
Dynodwyr
Cyfenwau	IL2RG, CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1, interleukin 2 receptor subunit gamma
Dynodwyr allanol	OMIM: 308380 HomoloGene: 172 GeneCards: IL2RG
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • interleukin-7 receptor activity • interleukin-2 receptor activity • GO:0001948, GO:0016582 protein binding • GO:0016518 cytokine receptor activity • interleukin-4 receptor activity • interleukin-2 binding • GO:0019974 cytokine binding • interleukin-15 receptor activity Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • integral component of plasma membrane • external side of plasma membrane • endosome • cytosol • cell surface • receptor complex Prosesau biolegol • MAPK cascade • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • GO:0022415 viral process • GO:0072468 signal transduction • interleukin-2-mediated signaling pathway • interleukin-4-mediated signaling pathway • interleukin-7-mediated signaling pathway • interleukin-15-mediated signaling pathway • interleukin-9-mediated signaling pathway • regulation of molecular function • cytokine-mediated signaling pathway • interleukin-21-mediated signaling pathway • positive regulation of phagocytosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3561	n/a
Ensembl	ENSG00000147168	n/a
UniProt	P31785	n/a
RefSeq (mRNA)	NM_000206	n/a
RefSeq (protein)	NP_000197	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn IL2RG yw IL2RG a elwir hefyd yn Interleukin 2 receptor subunit gamma (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xq13.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IL2RG.

• P64
• CIDX
• IMD4
• CD132
• SCIDX
• IL-2RG
• SCIDX1

Llyfryddiaeth

• "A novel deletion mutation in IL2RG gene results in X-linked severe combined immunodeficiency with an atypical phenotype. ". Immunogenetics. 2017. PMID 27566612.
• "New insights of common gamma chain in hematological malignancies. ". Cytokine. 2017. PMID 26748725.
• "The common γ-chain cytokine receptor: tricks-and-treats for T cells. ". Cell Mol Life Sci. 2016. PMID 26468051.
• "A novel common gamma chain mutation in a Chinese family with X-linked severe combined immunodeficiency (X-SCID; T(-)NK(-)B( )). ". Immunogenetics. 2015. PMID 26409833.
• "Late-Onset Combined Immunodeficiency with a Novel IL2RG Mutation and Probable Revertant Somatic Mosaicism.". J Clin Immunol. 2015. PMID 26407811.