FXR1

FXR1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CPQ, 3KUF, 3O8V
Dynodwyr
Cyfenwau	FXR1, FXR1P, FMR1 autosomal homolog 1, MYORIBF, MYOPMIL
Dynodwyr allanol	OMIM: 600819 HomoloGene: 3573 GeneCards: FXR1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • G-quadruplex RNA binding • mRNA 3'-UTR binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • nucleic acid binding • mRNA binding • RNA strand annealing activity • RNA binding • translation regulator activity Cydrannau o'r gell • bilen • ribonucleoprotein granule • dendritic spine • axon • dendrite • nucleolus • perinuclear region of cytoplasm • costamere • cnewyllyn cell • cytosol • cytoplasm • polysome • GO:0097483, GO:0097481 postsynaptic density • cytoplasmic ribonucleoprotein granule • soma • postsynapse • glutamatergic synapse Prosesau biolegol • cell differentiation • muscle organ development • multicellular organism development • GO:0097285 apoptotic process • GO:1905618 positive regulation of gene silencing by miRNA • negative regulation of translation • regulation of translation • regulation of mRNA stability • positive regulation of translation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8087	n/a
Ensembl	ENSG00000114416	n/a
UniProt	P51114	n/a
RefSeq (mRNA)	NM_001013438 NM_001013439 NM_005087 NM_001363882	n/a
RefSeq (protein)	NP_001013456 NP_001013457 NP_005078 NP_001350811	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn FXR1 yw FXR1 a elwir hefyd yn Fragile X mental retardation syndrome-related protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q26.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FXR1.

• FXR1P

Llyfryddiaeth

• "SplicePie: a novel analytical approach for the detection of alternative, non-sequential and recursive splicing. ". Nucleic Acids Res. 2015. PMID 25800735.
• "The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers. ". Proc Natl Acad Sci U S A. 2015. PMID 25733852.
• "RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC. ". PLoS Genet. 2016. PMID 27606879.
• "Regulation of monocyte induced cell migration by the RNA binding protein, FXR1. ". Cell Cycle. 2016. PMID 27229378.
• "A Specialized Mechanism of Translation Mediated by FXR1a-Associated MicroRNP in Cellular Quiescence.". Mol Cell. 2016. PMID 26942679.