CNR2

CNR2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2KI9
Dynodwyr
Cyfenwau	CNR2, CB-2, CB2, CX5, Cannabinoid receptor type 2, cannabinoid receptor 2
Dynodwyr allanol	OMIM: 605051 HomoloGene: 1389 GeneCards: CNR2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • G protein-coupled receptor activity • signal transducer activity • cannabinoid receptor activity Cydrannau o'r gell • integral component of membrane • perikaryon • cell projection • bilen • extrinsic component of cytoplasmic side of plasma membrane • Cellbilen • integral component of plasma membrane • soma • dendrite • neuron projection Prosesau biolegol • negative regulation of nitric-oxide synthase activity • negative regulation of mast cell activation • cannabinoid signaling pathway • response to amphetamine • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • negative regulation of action potential • response to lipopolysaccharide • negative regulation of synaptic transmission, GABAergic • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • sensory perception of pain • inflammatory response • negative regulation of inflammatory response • GO:0072468 signal transduction • leukocyte chemotaxis • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1269	n/a
Ensembl	ENSG00000188822	n/a
UniProt	P34972	n/a
RefSeq (mRNA)	NM_001841	n/a
RefSeq (protein)	NP_001832	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CNR2 yw CNR2 a elwir hefyd yn Cannabinoid receptor 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p36.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CNR2.

• CB2
• CX5
• CB-2

Llyfryddiaeth

• "Cannabinoid receptor 2-63 RR variant is independently associated with severe necroinflammation in HIV/HCV coinfected patients. ". PLoS One. 2017. PMID 28759568.
• "Emerging therapeutic targets in cancer induced bone disease: A focus on the peripheral type 2 cannabinoid receptor. ". Pharmacol Res. 2017. PMID 28274851.
• "CB2-63 polymorphism and immune-mediated diseases associated with HCV chronic infection. ". Dig Liver Dis. 2016. PMID 27476469.
• "Cannabinoid Receptor 2 as Antiobesity Target: Inflammation, Fat Storage, and Browning Modulation. ". J Clin Endocrinol Metab. 2016. PMID 27294325.
• "The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche.". PLoS One. 2015. PMID 26447698.