CCNT1

CCNT1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2PK2, 3BLH, 3BLQ, 3BLR, 3LQ5, 3MI9, 3MIA, 3MY1, 3TN8, 3TNH, 3TNI, 4BCF, 4BCG, 4BCH, 4BCI, 4BCJ, 4EC8, 4EC9, 4IMY, 4OGR, 4OR5
Dynodwyr
Cyfenwau	CCNT1, CCNT, CYCT1, HIVE1, cyclin T1
Dynodwyr allanol	OMIM: 143055 HomoloGene: 947 GeneCards: CCNT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • snRNA binding • chromatin binding • 7SK snRNA binding • cyclin-dependent protein serine/threonine kinase regulator activity • GO:0001948, GO:0016582 protein binding • RNA polymerase binding • transcription factor binding • protein serine/threonine kinase activity • protein kinase binding • GO:0016534 cyclin-dependent protein serine/threonine kinase activator activity Cydrannau o'r gell • nucleoplasm • nucleolus • cyclin/CDK positive transcription elongation factor complex • cnewyllyn cell • cyclin-dependent protein kinase holoenzyme complex Prosesau biolegol • regulation of cyclin-dependent protein serine/threonine kinase activity • negative regulation of mRNA polyadenylation • GO:0009373 regulation of transcription, DNA-templated • transcription elongation from RNA polymerase II promoter • transcription by RNA polymerase II • Cellraniad • protein phosphorylation • positive regulation of phosphorylation of RNA polymerase II C-terminal domain • positive regulation of cyclin-dependent protein serine/threonine kinase activity • positive regulation of viral transcription • cell cycle • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0022415 viral process • transcription, DNA-templated • snRNA transcription by RNA polymerase II • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1950094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • positive regulation of DNA-templated transcription, elongation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	904	n/a
Ensembl	ENSG00000129315	n/a
UniProt	O60563	n/a
RefSeq (mRNA)	NM_001240 NM_001277842	n/a
RefSeq (protein)	NP_001231 NP_001264771	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CCNT1 yw CCNT1 a elwir hefyd yn Cyclin T1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q13.11-q13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CCNT1.

• CCNT
• CYCT1
• HIVE1

Llyfryddiaeth

• "Computational study and peptide inhibitors design for the CDK9 - cyclin T1 complex. ". J Mol Model. 2013. PMID 23296566.
• "Modulation of intracellular restriction factors contributes to methamphetamine-mediated enhancement of acquired immune deficiency syndrome virus infection of macrophages. ". Curr HIV Res. 2012. PMID 22591364.
• "Preventing the formation of positive transcription elongation factor b by human cyclin T1-binding RNA aptamer for anti-HIV transcription. ". AIDS. 2012. PMID 22569018.
• "Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4 T lymphocytes. ". J Virol. 2012. PMID 22205749.
• "HIV-1 replication and latency are regulated by translational control of cyclin T1.". J Mol Biol. 2011. PMID 21763496.