ARFIP2

ARFIP2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1I49, 1I4D, 1I4L, 1I4T, 4DCN
Dynodwyr
Cyfenwau	ARFIP2, POR1, ADP ribosylation factor interacting protein 2
Dynodwyr allanol	OMIM: 601638 HomoloGene: 8234 GeneCards: ARFIP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphatidylinositol-4-phosphate binding • protein domain specific binding • GO:0001948, GO:0016582 protein binding • GTP binding • identical protein binding • cadherin binding • GTP-dependent protein binding • phospholipid binding Cydrannau o'r gell • cell cortex • trans-Golgi network membrane • Cellbilen • ruffle • cytosol • cytoplasm Prosesau biolegol • ruffle organization • small GTPase mediated signal transduction • actin cytoskeleton organization • regulation of Arp2/3 complex-mediated actin nucleation • lamellipodium assembly • intracellular protein transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23647	n/a
Ensembl	ENSG00000132254	n/a
UniProt	P53365	n/a
RefSeq (mRNA)	NM_001242854 NM_001242855 NM_001242856 NM_012402	n/a
RefSeq (protein)	NP_001229783 NP_001229784 NP_001229785 NP_036534 NP_001357335 NP_001357337 NP_001357338 NP_001357340 NP_001357341 NP_001357342 NP_001363487 NP_001363488 NP_001363489 NP_001363490 NP_001363491 NP_001363492 NP_001363493	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARFIP2 yw ARFIP2 a elwir hefyd yn ADP ribosylation factor interacting protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p15.4.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARFIP2.

• POR1

Llyfryddiaeth

• "Arfaptin 2 regulates the aggregation of mutant huntingtin protein. ". Nat Cell Biol. 2002. PMID 11854752.
• "The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. ". Nature. 2001. PMID 11346801.
• "Dimer of arfaptin 2 regulates NF-κB signaling by interacting with IKKβ/NEMO and inhibiting IKKβ kinase activity. ". Cell Signal. 2015. PMID 26296658.
• "Arf1 and membrane curvature cooperate to recruit Arfaptin2 to liposomes. ". PLoS One. 2013. PMID 23638170.
• "Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase.". J Biol Chem. 2012. PMID 22679020.