ANXA4

ANXA4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ZOC
Dynodwyr
Cyfenwau	ANXA4, ANX4, HEL-S-274, PIG28, ZAP36, P32.5, PAP-II, PP4-X, annexin A4
Dynodwyr allanol	OMIM: 106491 HomoloGene: 68164 GeneCards: ANXA4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phospholipase inhibitor activity • calcium ion binding • calcium-dependent protein binding • NF-kappaB binding • GO:0001948, GO:0016582 protein binding • identical protein binding • calcium-dependent phospholipid binding • heparin binding • chondroitin sulfate binding Cydrannau o'r gell • cytoplasm • nuclear membrane • vesicle membrane • Cellbilen • cell surface • perinuclear region of cytoplasm • extracellular exosome • cnewyllyn cell • cytosol • collagen-containing extracellular matrix Prosesau biolegol • Notch signaling pathway • epithelial cell differentiation • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1950094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • negative regulation of apoptotic process • negative regulation of NF-kappaB transcription factor activity • GO:0072468 signal transduction • GO:0048553 negative regulation of catalytic activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	307	n/a
Ensembl	ENSG00000196975	n/a
UniProt	P09525	n/a
RefSeq (mRNA)	NM_001153 NM_001320698 NM_001320700 NM_001320702 NM_001365496	n/a
RefSeq (protein)	NP_001144 NP_001307627 NP_001307629 NP_001307631 NP_001352425	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ANXA4 yw ANXA4 a elwir hefyd yn Annexin A4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ANXA4.

• ANX4
• P32.5
• PIG28
• PP4-X
• ZAP36
• PAP-II
• HEL-S-274

Llyfryddiaeth

• "The Role of Annexin A4 in Triple-Negative Breast Cancer Progression and Its Clinical Application. ". Ann Clin Lab Sci. 2016. PMID 27650619.
• "The role of annexin A4 in cancer. ". Front Biosci (Landmark Ed). 2016. PMID 27100483.
• "Overexpression of annexin A4 indicates poor prognosis and promotes tumor metastasis of hepatocellular carcinoma. ". Tumour Biol. 2016. PMID 26779633.
• "Annexin A4 and cancer. ". Clin Chim Acta. 2015. PMID 26048190.
• "Annexin A4 induces platinum resistance in a chloride-and calcium-dependent manner.". Oncotarget. 2014. PMID 25277200.