ADA

ADA
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3IAR
Dynodwyr
Cyfenwau	ADA, entrez:100, Adenosine deaminase, ADA1
Dynodwyr allanol	OMIM: 608958 HomoloGene: 37249 GeneCards: ADA
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• deaminase activity; • zinc ion binding; • metal ion binding; • hydrolase activity; • purine nucleoside binding; • GO:0001948, GO:0016582 protein binding; • adenosine deaminase activity;
Cydrannau o'r gell	• bilen; • cytoplasmic vesicle lumen; • cell surface; • cell junction; • soma; • dendrite cytoplasm; • GO:0016023 cytoplasmic vesicle; • external side of plasma membrane; • extracellular space; • cytoplasm; • lysosome; • cytosol; • Cellbilen;
Prosesau biolegol	• positive regulation of T cell differentiation; • histamine secretion; • negative regulation of circadian sleep/wake cycle, non-REM sleep; • purine nucleotide salvage; • positive regulation of T cell differentiation in thymus; • positive regulation of calcium-mediated signaling; • xanthine biosynthetic process; • response to hypoxia; • lung development; • placenta development; • deoxyadenosine catabolic process; • positive regulation of T cell receptor signaling pathway; • adenosine metabolic process; • purine-containing compound salvage; • dATP catabolic process; • GO:0010260 heneiddio; • negative regulation of thymocyte apoptotic process; • negative regulation of apoptotic process; • in utero embryonic development; • negative regulation of mature B cell apoptotic process; • nucleotide metabolic process; • response to vitamin E; • positive regulation of heart rate; • negative regulation of adenosine receptor signaling pathway; • response to morphine; • regulation of cell-cell adhesion mediated by integrin; • T cell activation; • cell adhesion; • positive regulation of T cell activation; • positive regulation of B cell proliferation; • trophectodermal cell differentiation; • regulation of circadian sleep/wake cycle, sleep; • hypoxanthine biosynthetic process; • purine ribonucleoside monophosphate biosynthetic process; • germinal center B cell differentiation; • liver development; • lung alveolus development; • Peyer's patch development; • negative regulation of mucus secretion; • inosine biosynthetic process; • positive regulation of smooth muscle contraction; • negative regulation of inflammatory response; • negative regulation of leukocyte migration; • positive regulation of germinal center formation; • positive regulation of alpha-beta T cell differentiation; • embryonic digestive tract development; • negative regulation of penile erection; • regulation of T cell differentiation; • response to hydrogen peroxide; • adenosine catabolic process; • hypoxanthine salvage;
	Sources:Amigo / QuickGO
Orthologau
	100
	n/a
	ENSG00000196839
	n/a
	P00813
	n/a
	NM_000022; NM_001322050; NM_001322051
	n/a
	NP_000013; NP_001308979; NP_001308980
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADA yw ADA a elwir hefyd yn Adenosine deaminase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.12.^[2]

Llyfryddiaeth

"Platelet aggregation and serum adenosine deaminase (ADA) activity in pregnancy associated with diabetes, hypertension and HIV. ". Cell Biochem Funct. 2016. PMID 27273565.
"Adenosine Deaminase - a Novel Diagnostic and Prognostic Biomarker for Oral Squamous Cell Carcinoma. ". Asian Pac J Cancer Prev. 2016. PMID 27221867.
"Elevated Serum ADA Activity as a Marker for Diagnosis and Prognosis of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis in Indian Patients. ". PLoS One. 2016. PMID 27186641.
"Can pleural adenosine deaminase (ADA) levels in pleural tuberculosis predict the presence of pulmonary tuberculosis? A CT analysis. ". Clin Radiol. 2016. PMID 27017482.
"Seed specific expression and analysis of recombinant human adenosine deaminase (hADA) in three host plant species.". Transgenic Res. 2016. PMID 26994767.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] ADA - Cronfa NCBI

[1]

[2]