ACHE

ACHE
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4EY7, 4PQE, 1F8U, 3LII, 4BDT, 4M0E, 4M0F, 1VZJ, 2X8B, 1B41, 4EY4, 4EY5, 4EY6, 4EY8, 5FOQ, 5HF9, 5HF6, 5FPQ, 5HF8, 5HFA
Dynodwyr
Cyfenwau	ACHE, AChE, acetylhydrolase, acetylcholinesterase (Yt blood group), ACEE, ARN-YT, acetylcholinesterase (Cartwright blood group), true cholinesterase (dated synonym)
Dynodwyr allanol	OMIM: 100740 HomoloGene: 543 GeneCards: ACHE
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • collagen binding • acetylcholine binding • serine hydrolase activity • GO:0004091 carboxylic ester hydrolase activity • amyloid-beta binding • cholinesterase activity • protein self-association • GO:0001948, GO:0016582 protein binding • laminin binding • hydrolase activity • ACHE • acetylcholinesterase activity Cydrannau o'r gell • Golgi apparatus • bilen • Cellbilen • synapse • extracellular region • cell surface • cell junction • perinuclear region of cytoplasm • anchored component of membrane • cnewyllyn cell • synaptic cleft • extracellular space • neuromuscular junction • basement membrane Prosesau biolegol • muscle organ development • receptor internalization • neurotransmitter biosynthetic process • negative regulation of synaptic transmission, cholinergic • amyloid precursor protein metabolic process • protein tetramerization • acetylcholine catabolic process • nervous system development • neurotransmitter catabolic process • DNA replication • cell adhesion • retina development in camera-type eye • response to wounding • positive regulation of protein secretion • osteoblast development • synapse assembly • phosphatidylcholine biosynthetic process • regulation of receptor recycling • cell population proliferation • acetylcholine catabolic process in synaptic cleft • positive regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	43	n/a
Ensembl	ENSG00000087085	n/a
UniProt	P22303	n/a
RefSeq (mRNA)	NM_000665 NM_001282449 NM_001302621 NM_001302622 NM_015831 NM_001367915 NM_001367917 NM_001367918 NM_001367919	n/a
RefSeq (protein)	NP_000656 NP_001269378 NP_001289550 NP_001289551 NP_001354844 NP_001354846 NP_001354847 NP_001354848	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sydd yn cael eu codio yn y corff dynol gan y genyn ACHE yw ACHE a elwir hefyd yn Acetylcholinesterase (Cartwright blood group) (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mae'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ACHE.

• YT
• ACEE
• ARACHE
• N-ACHE

Llyfryddiaeth

• "Targeting copper(II)-induced oxidative stress and the acetylcholinesterase system in Alzheimer's disease using multifunctional tacrine-coumarin hybrid molecules. ". J Inorg Biochem. 2016. PMID 27230386.
• "Intensified vmPFC surveillance over PTSS under perturbed microRNA-608/AChE interaction. ". Transl Psychiatry. 2016. PMID 27138800.
• "Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: mechanism and possible advantages for myasthenia gravis treatment. ". Biochem J. 2016. PMID 26929400.
• "A novel fluorogenic probe for the investigation of free thiols: Application to kinetic measurements of acetylcholinesterase activity. ". Toxicol Lett. 2016. PMID 26494253.
• "Oxidative stress and damage to erythrocytes in patients with chronic obstructive pulmonary disease--changes in ATPase and acetylcholinesterase activity.". Biochem Cell Biol. 2015. PMID 26369587.