Luc Henry

Luc Henry

Lausanne, Waadt, Schweiz
2814 Follower:innen 500  Kontakte

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Info

Curious by nature, I am constantly looking for challenges. I am the CEO and co-founder of…

Berufserfahrung

  • Limula Grafik

    Limula

    Lausanne, Vaud, Switzerland

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    Lausanne, Vaud, Switzerland

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    Lausanne, Vaud, Switzerland

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    Zurich

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    Lausanne Area, Switzerland

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    Lausanne, Vaud, Switzerland

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    Bern

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    Geneva Area, Switzerland

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    Basel Area, Switzerland

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    London, United Kingdom

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    Lausanne Area, Switzerland

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    Ulm Area, Germany

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    Lausanne Area, Switzerland

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    Greater London

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Ausbildung

  • University of Oxford Grafik

    University of Oxford

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    Activities and Societies: Member of Lincoln College, founder and first president of the Oxford Swiss Society, associate member of the Royal Society of Chemistry and member of the Swiss Chemical Society.

    My research at Oxford was mostly focused on synthetic organic chemistry and its application to enzymology. I worked on natural product biosynthesis in bacteria and drug mechanism of action in humans. I joined Lincoln College with a Lord Florey fellowship from the Berrow Foundation to carry out DPhil studies at the Chemistry department in the research group of Prof. Christopher J. Schofield FRS.

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    During my Master studies at EPFL, I specialised in Organic and Biological Chemistry, with a focus on how synthetic chemistry can provide tools to study biological systems. I spend 7 months at the University of Oxford to work on the rational design of new classes of PBP inhibitors as potential antibiotics, using in silico modelling and synthetic chemistry.

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    Activities and Societies: Member of Värmlands Nation (http://www.varmlandsnation.se)

    Joined the Chemistry and Biochemistry department on a scholarship from the Erasmus exchange program. I received training in Organic Chemistry, Analytical Chemistry, and Biochemistry

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    Course Goals and Objectives: Students who successfully completed this course were able to:
    - Describe the major steps of the drug and device development process from bench to bed-side.
    - Compare and contrast US and European Union regulatory and quality requirements.
    - Discuss the basics of a Quality Management System.
    - Develop a Product Profile for a drug/device product or therapy.
    - Draft the basic components of a Development Plan for a Phase 1 clinical trial, including a…

    Course Goals and Objectives: Students who successfully completed this course were able to:
    - Describe the major steps of the drug and device development process from bench to bed-side.
    - Compare and contrast US and European Union regulatory and quality requirements.
    - Discuss the basics of a Quality Management System.
    - Develop a Product Profile for a drug/device product or therapy.
    - Draft the basic components of a Development Plan for a Phase 1 clinical trial, including a Preclinical Plan, a Clinical Trial Protocol, and CMC Plan.
    - Work with other life science professionals on a team.

Bescheinigungen und Zertifikate

Ehrenamt

  • Hackuarium Grafik

    Co-founder and President

    Hackuarium

    – 5 Jahre 1 Monat

    Science and Technology

    I imagined and co-created the Hackuarium in the spring 2014. I subsequently led the association as its President over its first 3 years of existence, and later as its secretary for another 2 years. Hackuarium is an initiative that promotes open and collaborative research and development at the interface of biology, technology and the arts. It is a vibrant community of like-minded and curious people, biologists, engineers, computer scientists, but also artists, designers and other profiles…

    I imagined and co-created the Hackuarium in the spring 2014. I subsequently led the association as its President over its first 3 years of existence, and later as its secretary for another 2 years. Hackuarium is an initiative that promotes open and collaborative research and development at the interface of biology, technology and the arts. It is a vibrant community of like-minded and curious people, biologists, engineers, computer scientists, but also artists, designers and other profiles, ready to engage in challenging projects. It is also a physical laboratory where 'amateurs' can perform experiments and test their ideas with the support of other members of the community. More information here: http://wiki.hackuarium.ch/w/Main_Page

  • LIFT Grafik

    Event Assistant

    LIFT

    – 1 Monat

    Science and Technology

    To get a privileged insight into a world-class event that explores the business and social implications of technological innovation, I enrolled as a volunteer to help run the 2014 of the LIFT conference in Geneva (http://liftconference.com/lift14). I was responsible for welcoming participants from all over the world, and other practical aspects during the 3-days conference.

  • Life Sciences Switzerland (LS2) Grafik

    Conference Organizer and Chair

    Life Sciences Switzerland (LS2)

    – 2 Monaten

    Science and Technology

    I was in charge of organising, planning and chairing the Ethics session of the 2014 Life Science Switzerland annual meeting (http://www.ls2-annual-meeting.ch). This task included editorial work for building a scientific program, contacting potential speakers, coordinating the session, chairing the session and the roundtable that followed

Veröffentlichungen

  • Rebels or profiteers?

    Science / AAAS

    “Open,” the new black of political controversy, has become ubiquitous in contemporary
    debates surrounding scientific practices. Just as software activists managed to free
    information technologies from the realms of academia and industry, today some biologists
    believe their science would have a larger impact if carried out in the open. However, most
    scientists still have a narrow conception of where the “open revolution” comes from and what
    it means.

    Veröffentlichung anzeigen

  • The Enzymes of beta-lactam Biosynthesis

    Natural Product Reports

    The β-lactam antibiotics and related β-lactamase inhibitors are amongst the most important small molecules in clinical use. Most, but not all, β-lactams including penicillins, cephalosporins, and clavulanic acid are produced via fermentation or via modification of fermented intermediates, with important exceptions being the carbapenems and aztreonam. The desire for more efficient routes to existing antibiotics and for access to new and synthetically challenging ones stimulates continued…

    The β-lactam antibiotics and related β-lactamase inhibitors are amongst the most important small molecules in clinical use. Most, but not all, β-lactams including penicillins, cephalosporins, and clavulanic acid are produced via fermentation or via modification of fermented intermediates, with important exceptions being the carbapenems and aztreonam. The desire for more efficient routes to existing antibiotics and for access to new and synthetically challenging ones stimulates continued interest in β-lactam biosynthesis. We review knowledge of the pathways leading to β-lactam antibiotics focusing on the mechanisms, structures and biocatalytic applications of the enzymes involved.

    Andere Autor:innen
    Veröffentlichung anzeigen

  • Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

    Journal of the American Chemical Society

    Veröffentlichung anzeigen

  • Structural and mechanistic studies on γ-butyrobetaine hydroxylase

    Chemistry & Biology / Cell Press

    The final step in carnitine biosynthesis is catalyzed by γ-butyrobetaine (γBB) hydroxylase
    (BBOX), an iron/2-oxoglutarate (2OG) dependent oxygenase. BBOX is inhibited by
    trimethylhydrazine-propionate (THP), a clinically used compound. We report structural and
    mechanistic studies on BBOX and its reaction with THP. Crystallographic and sequence
    analyses reveal that BBOX and trimethyllysine hydroxylase form a subfamily of 2OG
    oxygenases that dimerize using an N-terminal domain.

    Andere Autor:innen
    Veröffentlichung anzeigen

Sprachen

  • English

    Muttersprache oder zweisprachig

  • French

    Muttersprache oder zweisprachig

  • German

    Gute Kenntnisse

  • Swedish

    Grundkenntnisse

  • Italian

    Grundkenntnisse

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