„I have known Antonio for 5 years. We collaborated on confocal measurements of fluorescent protein absorbtion on TiOx substrates at the Cimaina (interdisciplinary center of nanostructured materials and interfaces), University of Milan. We also worked togheter on the creation of a FRET experiment data analysis plug-in. Working with Antonio was both a rewarding and a pleasurable experience. I am confident that Antonio will demonstrait the highest level of enthusiasm, commitment and intelligence in whatever endevour he becomes involved in.“
Aktivitäten
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Nel settore degli investimenti in #PrivateAssets, i laureati in #Ingegneria, in particolare #Gestionale, sono tra i più ricercati per l’adeguata…
Nel settore degli investimenti in #PrivateAssets, i laureati in #Ingegneria, in particolare #Gestionale, sono tra i più ricercati per l’adeguata…
Beliebt bei Antonio Borgonovo
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The ECB recently cut interest rates by 0.25% in response to falling inflation. This decision offers new economic prospects, although a return to…
The ECB recently cut interest rates by 0.25% in response to falling inflation. This decision offers new economic prospects, although a return to…
Beliebt bei Antonio Borgonovo
Berufserfahrung
Ausbildung
Veröffentlichungen
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Direct Microfabrication of Topographical and Chemical Cues for the Guided Growth of Neural Cell Networks on Polyamidoamine Hydrogels
Macromolecular Bioscience
Cell patterning is an important tool for organizing cells in surfaces and to reproduce in a simple way the tissue hierarchy and complexity of pluri-cellular life. The control of cell growth, proliferation and differentiation on solid surfaces is consequently important for prosthetics, biosensors, cell-based arrays, stem cell therapy and cell-based drug discovery concepts. We present a new electron beam lithography method for the direct and simultaneous fabrication of sub-micron topographical…
Cell patterning is an important tool for organizing cells in surfaces and to reproduce in a simple way the tissue hierarchy and complexity of pluri-cellular life. The control of cell growth, proliferation and differentiation on solid surfaces is consequently important for prosthetics, biosensors, cell-based arrays, stem cell therapy and cell-based drug discovery concepts. We present a new electron beam lithography method for the direct and simultaneous fabrication of sub-micron topographical and chemical patterns, on a biocompatible and biodegradable PAA hydrogel. The localized e-beam modification of a hydrogel surface makes the pattern able to adsorb proteins in contrast with the anti-fouling surface. By also exploiting the selective attachment, growth and differentiation of PC12 cells, we fabricated a neural network of single cells connected by neuritis extending along microchannels. E-beam microlithography on PAA hydrogels opens up the opportunity of producing multifunctional microdevices incorporating complex topographies, allowing precise control of the growth and organization of individual cells.
Andere Autor:innenVeröffentlichung anzeigen -
The Effect of Surface Nanometre-Scale Morphology on Protein Adsorption
Plos One
Protein adsorption is the first of a complex series of events that regulates many phenomena at the nano-bio interface, e.g. cell adhesion and differentiation, in vivo inflammatory responses and protein crystallization. A quantitative understanding of how nanoscale morphology influences protein adsorption is strategic for providing insight into all of these processes, however this understanding has been lacking until now.
Here we introduce novel methods for quantitative high-throughput…Protein adsorption is the first of a complex series of events that regulates many phenomena at the nano-bio interface, e.g. cell adhesion and differentiation, in vivo inflammatory responses and protein crystallization. A quantitative understanding of how nanoscale morphology influences protein adsorption is strategic for providing insight into all of these processes, however this understanding has been lacking until now.
Here we introduce novel methods for quantitative high-throughput characterization of protein-surface interaction and we apply them in an integrated experimental strategy, to study the adsorption of a panel of proteins on nanostructured surfaces. We show that the increase of nanoscale roughness (from 15 nm to 30 nm) induces a decrease of protein binding affinity (≤90%) and a relevant increase in adsorbed proteins (≤500%) beyond the corresponding increase of specific area. We demonstrate that these effects are caused by protein nucleation on the surface, which is promoted by surface nanoscale pores.
These results show that the adsorption of proteins depends significantly on surface nanostructure and that the relevant morphological parameter regulating the protein adsorption process is the nanometric pore shape. These new findings improve our understanding of the role of nanostructures as a biomaterial design parameter and they have important implications for the general understanding of cell behavior on nanostructured surfaces.Andere Autor:innenVeröffentlichung anzeigen
Projekte
Auszeichnungen/Preise
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Winner of Venture Capital Investment Italian Competition (VCIC Lite)
SDA Bocconi
http://www.vcic.unc.edu/organizers.internal.asp
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BCG Scholarship MBA 2013 SDA Bocconi
The Boston Consulting Group
Prüfungsergebnisse
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GMAT
Prüfungsergebnis: 730/800
96th percentile
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TOEFL
Prüfungsergebnis: 105/120
Sprachen
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English
Verhandlungssicher
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Italian
Muttersprache oder zweisprachig
Organisationen
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SDA Bocconi Consulting Club
President
–Heute
Erhaltene Empfehlungen
2 Personen haben Antonio Borgonovo empfohlen
Jetzt anmelden und ansehenWeitere Aktivitäten von Antonio Borgonovo
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Undoubtedly one of the most inspirational coaches of all-time, and not just in sports. 3 years ago we had the privilege of spending a few hours with…
Undoubtedly one of the most inspirational coaches of all-time, and not just in sports. 3 years ago we had the privilege of spending a few hours with…
Beliebt bei Antonio Borgonovo
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Today Italy won the Olympic Gold Medal in female Volleyball. A true Team, coached by a myth like Julio Velasco, supported in his staff by another…
Today Italy won the Olympic Gold Medal in female Volleyball. A true Team, coached by a myth like Julio Velasco, supported in his staff by another…
Beliebt bei Antonio Borgonovo
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At YELDO, we truly value the importance of a break, especially after a busy year full of projects and achievements. Taking time to recharge is…
At YELDO, we truly value the importance of a break, especially after a busy year full of projects and achievements. Taking time to recharge is…
Beliebt bei Antonio Borgonovo
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Yeldo Crowd chiude raccolta da 3,3 mln per un progetto a Courmayeur – Re2bit https://lnkd.in/dBZDXZru YELDO CROWD
Yeldo Crowd chiude raccolta da 3,3 mln per un progetto a Courmayeur – Re2bit https://lnkd.in/dBZDXZru YELDO CROWD
Beliebt bei Antonio Borgonovo
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Con una raccolta complessiva di 3,3 milioni di euro si è conclusa con successo Courmayeur, Via Regionale, l'ultima campagna di crowdfunding…
Con una raccolta complessiva di 3,3 milioni di euro si è conclusa con successo Courmayeur, Via Regionale, l'ultima campagna di crowdfunding…
Beliebt bei Antonio Borgonovo
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SAVE THE DATE! Diego Bortot, Chief Asset Management Real Estate and Servicing di Zenith Global S.p.A., parteciperà come relatore al convegno sulla…
SAVE THE DATE! Diego Bortot, Chief Asset Management Real Estate and Servicing di Zenith Global S.p.A., parteciperà come relatore al convegno sulla…
Beliebt bei Antonio Borgonovo
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WISE SpA (#LSIAlumni) raised a €25 million financing round, comprised of both equity investment and a venture debt loan from the European Investment…
WISE SpA (#LSIAlumni) raised a €25 million financing round, comprised of both equity investment and a venture debt loan from the European Investment…
Beliebt bei Antonio Borgonovo
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Siamo felici di annunciare la nostra prima exit sul progetto di Milano, Missori. Dopo solo 11 mesi dall'inizio dell'operazione, in anticipo rispetto…
Siamo felici di annunciare la nostra prima exit sul progetto di Milano, Missori. Dopo solo 11 mesi dall'inizio dell'operazione, in anticipo rispetto…
Beliebt bei Antonio Borgonovo
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YELDO CROWD, piattaforma di equity crowdfunding del Gruppo YELDO, specializzato nella raccolta di capitali per operazioni immobiliari di livello…
YELDO CROWD, piattaforma di equity crowdfunding del Gruppo YELDO, specializzato nella raccolta di capitali per operazioni immobiliari di livello…
Beliebt bei Antonio Borgonovo
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WISE SpA completa un #round di finanziamento 25 milioni di euro 📢📢 Azienda all’avanguardia nel settore dei #dispositivi #medici specializzata in…
WISE SpA completa un #round di finanziamento 25 milioni di euro 📢📢 Azienda all’avanguardia nel settore dei #dispositivi #medici specializzata in…
Beliebt bei Antonio Borgonovo
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