Notch Therapeutics

2024 has brought a new era of cell therapy for Notch, culminating in two accepted abstracts at the American Society of Hematology Annual Meeting. Our CSO, Christopher Bond, gives us an overview of the abstracts and a 2024 update in this video.   You can also read our press release here: https://lnkd.in/gmxhJmuk   And, you can read the abstracts online with the links below. They will each be presented as posters in December during the ASH Meeting in San Diego, CA. If you are attending ASH, please visit our scientists at the poster presentations detailed below, or reach out to set up a meeting with our team. 1. A Layered Cloaking Strategy to Generate Allogeneic iPSC-Derived CD8 T-Cells That Evade NK Clearance: https://lnkd.in/gvWXNdCR Saturday, December 7, 2024 from 5:30pm to 7:30pm    2. A Regulated Cytokine Engineering Strategy to Augment in Vitro and In Vivo Persistence of Allogeneic iPSC Derived CD8 T-Cells: https://lnkd.in/g-sxjr_D Monday, December 9, 2024 from 6:00pm to 8:00pm    #ASH2024 #ASH24 #CARTcell #cancer #celltherapy #tcells #Notchcelltherapy #iPSC

In Q3, Notch’s Culture and Engagement Committees worked diligently to organize events and share insights on key topics. Their efforts enhanced our understanding and appreciation of diverse cultures, strengthened community connections, fostered a fun and inclusive workplace, and encouraged us to lead healthier, more balanced lives. Quarter Highlights:  - DEIB Summer Reading List  - Education on the National Day for Truth and Reconciliation, spotlighting Indigenous Art including learning the meaning behind the mural on our Vancouver site building.  - Book Swap and Donation in celebration of International Literacy Day  - Monthly Social Events, including Ice Cream Day and the “Grill the EC” summer BBQ, where we asked fun and insightful questions to our EC members  - Wellness Initiatives, such as Bike Bingo, Step Challenge, and 30-Day Mental Health Challenge in October for World Mental Health Day    We are deeply grateful for the dedication of our Committees:  1. Diversity, Equity, Inclusion, and Belonging (DEIB): Education, awareness, and sharing insights on key cultural and social events.  2. Community and Philanthropy (C P): Strengthening connections through community engagement and outreach.  3. Party Pack: Building camaraderie to the workplace through fun social events.  4. Wellness Committee: Prioritizing personal well-being through health-focused activities. 

Notch created the Top Notch Awards to reinforce our core values by recognizing employees whose exceptional contributions go above and beyond, and positively impact the success of our company.   Each quarter, our Top Notch Committee—comprised of Directors from across the organization—carefully reviews peer nominations and selects the winners.   We're excited to celebrate the incredible Q3 winners! Join us in congratulating these outstanding individuals! Richard Carpenedo, Katrina K., Vignesh Janardhanam and Irja Elliott Donaghue

In Canada, September 30 marks the National Day for Truth and Reconciliation. It is also known as Orange Shirt Day. The day honours the children who never returned home and the survivors of residential schools, as well as their families and communities. Public commemoration of the tragic and painful history and ongoing impacts of residential schools is a vital component of the reconciliation process.   Today, we’ve encouraged our team members in Vancouver, Ontario, and Seattle to: 1. Learn more about Indigenous Art, including mural on the outside of our Vancouver office building: https://lnkd.in/gvTgFJDV 2. Listen to the Gord Downie & Chanie Wenjack Day to Listen broadcast: https://lnkd.in/e_47PJe 3. Wear Orange in recognition and remembrance.   We encourage you to also make time to learn and reflect – not just today, but as a regular practice.

On October 8th, David Main will present at Alliance for Regenerative Medicine's 2024 Cell & Gene Meeting on the Mesa in Phoenix, Arizona. Amanda M. Rickard and Timothy Key will also attend. If you are interested in partnering meetings, please reach out. #cellandgenetherapy #CGMesa24

Notch Therapeutics is hiring! We are seeking a Research Associate I, Preclinical Sciences who will support discovery research by interfacing with Cancer Biology and Cell Engineering groups of Notch in Seattle. This individual will be responsible for advancing Notch’s discovery pipeline by performing experiments within the cancer biology group while working closely with other members of the cell therapy team in Seattle. To learn more about this exciting opportunity, click the link below! https://lnkd.in/ecmsDi9a

Amanda M. Rickard will at the CAR-TCR Summit Series in Boston next week from September 17-20. If you'd like to meet, please reach out. #tcell #immunotherapy #celltherapy #CARTCR

On Tuesday, September 10, our CSO, Christopher Bond, is participating in the 'Development in Autoimmune Disease and Oncology & Beyond' panel at the SPICI (Smart People in Cellular Immunotherapy) Symposium which is presented by Chardan and sponsored by ElevateBio. We hope you can join us! #celltherapy #cellularimmunotherapy

At Notch Therapeutics, we are proud of our vibrant Culture and Engagement Committees which include: 1. Diversity, Equity, Inclusion and Belonging (DEIB) focusing on education and awareness and researching and sharing information on significant cultural and social events. 2. Community and Philanthropy (C P) cultivating community connections. 3. Party Pack bringing joy and camaraderie to our workplace by hosting monthly social events. 4. Wellness Committee emphasizing personal well-being. These dedicated teams have worked tirelessly this past quarter to organize events and share valuable information on important topics. Their efforts have enriched our understanding and appreciation of diverse cultures and histories, strengthened our community bonds, fostered a fun and inclusive work environment, and encouraged us to lead healthier, more balanced lives. Highlights from the Quarter: • Education about Ramadan, Nowruz, International Women’s Day, Vaisakhi, Victoria Day, Memorial Day, Pride, and Juneteenth.  • Park clean-up event near each of our sites in celebration of Earth Day. • Social events for National Employee Appreciation Day, National Cereal Day, Easter, and a thrilling Ping Pong Tournament at our Seattle site. • Resources and education about the benefits of sleep and supporting participation in local Spring Runs. We are immensely grateful for the dedication and hard work of our committees here at Notch Therapeutics. 

Notch created our Top Notch Awards program to support and strengthen Notch Values by recognizing and rewarding employees for outstanding accomplishments and contributions that exceed expectations and positively impacts the success of the company.  Our Top Notch Committee, composed of Directors across the organization, review nominations submitted by colleagues each quarter and determine the winners. We are proud to celebrate the winners from the first half of 2024 below. Help us congratulate these Top Notch individuals! Julia Bershadsky, Justin Yoo, Laura Prochazka, Chloe Hurling, Chris Saxby, Elisa Martinez