S Wikipedije, slobodne enciklopedije
U molekulskoj biologiji, urotelno vezani karcinom 1 (neproteinsko kodiranje), poznat i kao UCA1 , duga nekodirajuća RNK , pojačano je regulirana kod karcinoma mokraćne bešike .[ 3] embryonic development and in bladder cancer invasion and progression. It regulates the expression of several genes involved in tumourgenesis and/or embryonic development.[ 4]
Vjeruje se da djeluje u regulaciji embrionskog razvoja i invazije i napredovanja karcinoma mokraćne bešike . Regulira ekspresija nekoliko gena , uključenih u tumurgenezu i/ili razvoj embriona .[ 4]
^ a b c GRCh38: Ensembl release 89: ENSG00000214049 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Wang XS, Zhang Z, Wang HC, Cai JL, Xu QW, Li MQ, Chen YC, Qian XP, Lu TJ, Yu LZ, Zhang Y, Xin DQ, Na YQ, Chen WF (2006). "Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma" . Clinical Cancer Research . 12 (16): 4851–8. doi :10.1158/1078-0432.CCR-06-0134 PMID 16914571 . ^ a b Wang F, Li X, Xie X, Zhao L, Chen W (2008). "UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion" . FEBS Letters . 582 (13): 1919–27. doi :10.1016/j.febslet.2008.05.012 PMID 18501714 . S2CID 207691688 .
Xie XJ, Li X, Wang F, Chen W (2010). "Cellular localization and tissue expression pattern of UCA1, a non-coding RNA" [Cellular localization and tissue expression pattern of UCA1, a non-coding RNA] (PDF) . 南方医科大学学报 [Journal of Southern Medical University] (jezik: Chinese). 30 (1): 57–60. PMID 20117985 . Arhivirano s originala (PDF) , 3. 3. 2016. Pristupljeno 27. 5. 2021 . CS1 održavanje: nepoznati jezik (link ) Kaneko K, Ito Y, Ono Y, Tainaka T, Tsuchiya H, Shimoyama Y, Ando H (2011). "Gene expression profiling reveals upregulated UCA1 and BMF in gallbladder epithelia of children with pancreaticobiliary maljunction". Journal of Pediatric Gastroenterology and Nutrition . 52 (6): 744–50. doi :10.1097/MPG.0b013e318214bd30 . PMID 21593646 . S2CID 44798828 . 
