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TTC28

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TTC28
Identifikatori
AliasiTTC28
Vanjski ID-jeviOMIM: 615098 MGI: 2140873 HomoloGene: 41023 GeneCards: TTC28
Lokacija gena (čovjek)
Hromosom 22 (čovjek)
Hrom.Hromosom 22 (čovjek)[1]
Hromosom 22 (čovjek)
Genomska lokacija za TTC28
Genomska lokacija za TTC28
Bend22q12.1Početak27,978,014 bp[1]
Kraj28,679,840 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za TTC28
Genomska lokacija za TTC28
Bend5|5 FPočetak111,027,669 bp[2]
Kraj111,437,646 bp[2]
Ontologija gena
Molekularna funkcija kinase binding
Ćelijska komponenta citoplazma
centar organizacije mikrotubula
Diobeno vreteno
spindle pole
citoskelet
midbody
mitotic spindle
Biološki proces ćelijski ciklus
Ćelijska dioba
regulation of mitotic cell cycle
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001145418
NM_015281
NM_001393403
NM_001393404
NM_001393405

NM_001267622
NM_024477

RefSeq (bjelančevina)

NP_001138890

NP_001254551

Lokacija (UCSC)Chr 22: 27.98 – 28.68 MbChr 5: 111.03 – 111.44 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Tetratrikopeptid ponavljajući domen 28 jest protein koji je kod ljudi kodiran genom TTC28 sa hromosoma 22.[5]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 2.481 aminokiselina, a molekulska težina 270.884 Da. [5]

1020304050
MEQSPPPAPEPTQGPTPARSRRRREPESPPASAPIPLFGADTIGQRSPDG
PVLSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSA
AYMKIQQYDKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFA
SGLAQDPKSLQLLVGMVEAAMKSPMRDSLEPTYQQLQKMKLDKSPFVVVS
VVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAYWSLGNT
EKSTGYMQQDLDVAKTLGDQTGECRAHGNLGSAFFSKGNYREALTNHRHQ
LVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDE
LSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNL
GSAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDL
ERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTH
LCIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDR
ASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNL
GNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNY
QEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYL
LSLAQSLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDR
RLEASAYAALGTAYRMIQKYDKALGYHTQELEVYQELSDLPGECRAHGHL
AAVYMALGKYTMAFKCYEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVM
EEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYY
EQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHEL
GEAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAA
CGLGGVYQQMGEYDTALQYHQLDLQIAEETNNPTCQGRAYGNLGLTYESL
GTFERAVVYQEQHLSIAAQMNDLAAKTVSYSSLGRTHHALQNYSQAVMYL
QEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETI
RHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAF
ADLLVERQTGQQDSDPYSPVTIDQILEMVNGQRGLVLYYSLAAGYLYSWL
LAPGAGIVKFHEHYLGENTVENSSDFQASSSVTLPTATGSALEQHIASVR
EALGVESHYSRACASSETESEAGDIMDQQFEEMNNKLNSVTDPTGFLRMV
RRNNLFNRSCQSMTSLFSNTVSPTQDGTSSLPRRQSSFAKPPLRALYDLL
IAPMEGGLMHSSGPVGRHRQLILVLEGELYLIPFALLKGSSSNEYLYERF
GLLAVPSIRSLSVQSKSHLRKNPPTYSSSTSMAAVIGNPKLPSAVMDRWL
WGPMPSAEEEAYMVSELLGCQPLVGSVATKERVMSALTQAECVHFATHIS
WKLSALVLTPSMDGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPP
LQELLLTAADVLDLQLPVKLVVLGSSQESNSKVTADGVIALTRAFLAAGA
QCVLVSLWPVPVAASKMFIHAFYSSLLNGLKASAALGEAMKVVQSSKAFS
HPSNWAGFMLIGSDVKLNSPSSLIGQALTEILQHPERARDALRVLLHLVE
KSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPPTSGLP
AAVFFPTSDPGDRLQQCSSTLQSLLGLPNPALQALCKLITASETGEQLIS
RAVKNMVGMLHQVLVQLQAGEKEQDLASAPIQVSISVQLWRLPGCHEFLA
ALGFDLCEVGQEEVILKTGKQANRRTVHFALQSLLSLFDSTELPKRLSLD
SSSSLESLASAQSVSNALPLGYQQPPFSPTGADSIASDAISVYSLSSIAS
SMSFVSKPEGGSEGGGPGGRQDHDRSKNAYLQRSTLPRSQLPPQTRPAGN
KDEEEYEGFSIISNEPLATYQENRNTCFSPDHKQPQPGTAGGMRVSVSSK
GSISTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQ
EESNPKLDPQELAQKILEETQSHLIAVERLQRSGGQVSKSNNPEDGVQAP
SSTAVFRASETSAFSRPVLSHQKSQPSPVTVKPKPPARSSSLPKVSSGYS
SPTTSEMSIKDSPSQHSGRPSPGCDSQTSQLDQPLFKLKYPSSPYSAHIS
KSPRNMSPSSGHQSPAGSAPSPALSYSSAGSARSSPADAPDIDKLKMAAI
DEKVQAVHNLKMFWQSTPQHSTGPMKIFRGAPGTMTSKRDVLSLLNLSPR
HNKKEEGVDKLELKELSLQQHDGAPPKAPPNGHWRTETTSLGSLPLPAGP
PATAPARPLRLPSGNGYKFLSPGRFFPSSKC

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100154 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033209 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: Tetratricopeptide repeat domain 28".

Dopunska literatura

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