New approach methodologies (NAMs) are gaining momentum. NAM Journal therefore comes at the right time! The newly established NAM Journal is supported by an editorial board consisting of experts from all over the world knowledgeable about the various aspects of NAMs. Please consider submitting your NAM papers to NAM Journal. Open access fees are waived for the next 2 years. https://lnkd.in/exXcCnHG
ONTOX
Research Services
EU-funded project advancing human risk assessment of chemicals with NAMs approaches.
About us
The vision of the ONTOX consortium is to provide a functional and sustainable solution for advancing human risk assessment of chemicals without the use of animals in line with the principles of 21st-century toxicity testing and next-generation risk assessment. This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No. 963845 The content of the ONTOX LinkedIn page is the sole responsibility of the ONTOX project and does not necessarily reflect the opinion of the EU.
- Website
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https://ontox-project.eu
External link for ONTOX
- Industry
- Research Services
- Company size
- 51-200 employees
- Headquarters
- Brussels
- Type
- Partnership
Locations
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Primary
Brussels, BE
Employees at ONTOX
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Joerg Marusczyk
Chief Technology Officer of MN-AM and for software sustainability at ONTOX
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Francois Busquet , PhD
Making Alternatives to Animal Testing a Reality
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Helena Kandarova, ERT
ESTIV President | Director at IEPT at CEM | Member of the Executive Board at CEM at SAS | ONTOX Deputy coordinator communication, dissemination &…
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Stephan Schaller
Your Partner for PBK and QSP/T | MIDD, NGRA and NAM | Translational Sciences | CEO @ esqLABS
Updates
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Happy to share this wonderful document on key recommendations from the Multi-stakeholder Roundtable on the EC Roadmap towards phasing out animal testing for chemical safety assessments from June 18, 2024. #ONTOX, #PrecisionTox and #RISKHunt3R - united in #ASPIS cluster were there and contributed to the content of this important document! Many thanks to the organisers for approaching our scientists with this important topic! #alternatives #EC #policies #toxicology #chemicals Michael Guy Diemar, Helena Kandarova, ERT, Francois Busquet , PhD, Giorgia Pallocca,
Passionate about animal welfare, advocating for the phase out of animal testing (EU and beyond) via a strengthened chemicals strategy. Firm supporter of equal North-South development efforts.
Looking for a Friday read?🧬 well the Flash Report from the Roundtable on the Commission #Roadmap is out, lucky you!!! (Please share!❤️)⭐️⚡️😎 🧬⚡️The document shares key recommendations from the Multi-stakeholder Roundtable on the EC Roadmap towards phasing out animal testing for chemical safety assessments from June 18, 2024. ✅ A true multi-stakeholder day: with 41 participants from the EU institutions, agencies, Member states, associations, academia, research centres and NGOs, the recommendations aim to share key points from all different voices. ✅ All about timing!⭐️ the file is set to help inform participants to the upcoming II EC Workshop on the Roadmap, this October 25, 2024. The more aligned we are, the better the discussions and greater the potential for change! ✅ Public Consultation? Yes!⭐️ if keen to support this EU-level historical movement to accelerate the phase-out of animal testing for safety assessments, feel free to read the Report for your feedback on the EC Consultation for the Roadmap. Deadline: 15 October, 2024. Thank you to the 5 NGOs who organised this Roundtable. And to the great professionals who joined and spoke up to find a common way forward with EU in the lead. #chemicals #chemicalsafety #animaltesting #safety #protection #environment #humanhealth #europe #europeanunion European Commission European Chemicals Agency European Medicines Agency EU Science, Research and Innovation European Society of Toxicology in Vitro ESTIV ASPIS EPAA European Partnership for Alternative Approaches Gavin Maxwell, Elisabet Berggren, Matthias Herzler, Jelle Vriend, Helena Kandarova, ERT, Francois Busquet , PhD, Laura Holden and many others! Eurogroup for Animals European Coalition To End Animal Experiments Humane Society International - Europe PETA Science Consortium International e.V. Cruelty Free International Luísa Ferreira Bastos A deep thank you to Laurence Walder and Giorgia Pallocca for leading the work❤️🐰🐹🐭
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🎉 Reflecting on the news from the ASPIS Open Symposium 2024! We’re thrilled to announce that Alessio Gamba, representing ONTOX, has been awarded the Best Poster Award! 🏆 This prestigious recognition grants him free entry to the European Society of Toxicology in Vitro ESTIV Congress 2026 in Maastricht. In Alessio's words: "I am thrilled to have won the ASPIS Open Symposium Best Poster Award. It is an important recognition for the whole team collaborating with me on the development of the Ontology and Physiological Map, two pillars of the ONTOX project. I look forward to attending and meeting you at the ESTIV Congress 2026 in Maastricht." A big congratulations to Alessio and his entire team for their hard work and innovation! 🌟 #ONTOX #ASPIS2024 #BestPosterAward #YoungScientists #ESTIV2026 #Toxicology #Innovation #Collaboration
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🌍Happy #WorldAnimalDay!🐾 On this special day, we celebrate 🐁animals by reaffirming our dedication to ✅reducing and ultimately ❌eliminating their use in 🥼science. Our #ONTOX scientists are 🤝committed to a future where scientific 💡innovation leads the way to safer 🧪chemical testing without the need for animal testing. ONTOX's mission is to 🚀advance human 📊risk assessment using cutting-edge, 👍animal-free methods aligned with the principles of 21st-century toxicity testing. Together, we can ✨create a more sustainable and humane future for 💙all living beings. 📝Subscribe to the ONTOX newsletter to learn more about our groundbreaking work towards animal-free chemical testing 👉 https://lnkd.in/d_V2Pqtj #AnimalFreeTesting #Toxicology #NAMs
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ONTOX reposted this
Join us for an engaging interview with Florian Caiment, Chair of the ASPIS Omics Working Group, as he delves into the world of omics analysis and big data. Discover: 🔍 The working group's focus and the importance of coordinating bioinformaticians across the three consortia (ONTOX, PrecisionTox and RISK-HUNT3R). 📈 Achievements so far, including upcoming publications. 🚀 Future goals to integrate omics into the regulatory landscape.
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The European researcher nights are excellent platforms for spreading the innovation to general public! Last week #CEM team from Slovakia presented the innovative approaches implemented at their workplace and promoted the #ONTOX and #ASPIS concepts to general public attending the fair. A lot of questions were related to the practical use of #AI and machine learning in the field of toxicology and personalised medicine.
ESTIV President | Director at IEPT at CEM | Member of the Executive Board at CEM at SAS | ONTOX Deputy coordinator communication, dissemination & exploitation | Bioscience Steering Panel EASAC | EPAA MG member | CEO
#ResearchersNight, or in Slovak, "Noc Vyskumnikov", is the biggest science festival in Slovakia. The festival is traditionally held on the last Friday of September in Bratislava, Košice, Banská Bystrica, Žilina, Poprad, and other accompanying locations. The day-long program (9 am to 11 pm) offers a series of scientific presentations, discussions, practical experiments, workshops, technological attractions, and digital activities. I am happy that our Institute of Experimental Pharmacology and Toxicology, CEM, Slovak Academy of Sciences, was represented by our excellent popularisation teams, formed mainly by our PhD students and early career scientists. A photo of my two team members from SK-NETVAL lab is attached - proud of you Klára Gabrišová and Peter Pôbiš! Many thanks also to Marek Lepáček, Pavol Boďo, @Milica Jahelková and our popularisation superstar, Dr Marta Prnova from the neighbouring lab, for presenting the research conducted at our Institute and Centre.
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ONTOX reposted this
We're excited to announce two important events in Brussels this month! 📅 𝟐𝟒 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 "𝐀𝐒𝐏𝐀, 𝐦𝐚𝐤𝐢𝐧𝐠 𝐧𝐞𝐱𝐭-𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐨𝐧 𝐫𝐢𝐬𝐤 𝐚𝐬𝐬𝐞𝐬𝐬𝐦𝐞𝐧𝐭 𝐡𝐚𝐩𝐩𝐞𝐧" meeting organised by RISK-HUNT3R, on behalf of the #ASPIScluster (RISK-HUNT3R, ONTOX, PrecisionTox). Learn more about #ASPA, the interactive #NGRA workflow guiding users through the entire #riskassessment process. This session will give the chance to directly engage with our experts, and share valuable insights ahead of the European Commission roadmap event the next day. R𝐞𝐠𝐢𝐬𝐭𝐞𝐫 here 👉 https://lnkd.in/etJhJ8VD. 📅 𝟐𝟓 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 🇪🇺 The 2nd workshop on 𝐑𝐨𝐚𝐝𝐦𝐚𝐩 𝐭𝐨𝐰𝐚𝐫𝐝𝐬 𝐩𝐡𝐚𝐬𝐢𝐧𝐠 𝐨𝐮𝐭 𝐚𝐧𝐢𝐦𝐚𝐥 𝐭𝐞𝐬𝐭𝐢𝐧𝐠 𝐟𝐨𝐫 𝐜𝐡𝐞𝐦𝐢𝐜𝐚𝐥 𝐬𝐚𝐟𝐞𝐭𝐲 𝐚𝐬𝐬𝐞𝐬𝐬𝐦𝐞𝐧𝐭𝐬, as part of the European Commission's response to the European Citizens' Initiative (ECI) "Save Cruelty-free Cosmetics - Commit to a Europe without Animal Testing", will feature our expert Sylvia. Escher presenting updates on the #ASPA workflow. Details here 👉 https://lnkd.in/dus3YiJy. 📢 Only 𝟗 𝐝𝐚𝐲𝐬 𝐥𝐞𝐟𝐭 𝐭𝐨 𝐫𝐞𝐠𝐢𝐬𝐭𝐞𝐫 for these back-to-back events! #NonAnimalMethods #chemical #regulations #Horizon2020 European Health and Digital Executive Agency (HaDEA)
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ONTOX reposted this
👏 The VICT3R project kicked off with an inspiring meeting in Barcelona on 26-27 September 2024! With over 70 attendees in person and more than 50 joining online, the enthusiasm and commitment to this transformative project were palpable. From the outset, participants engaged in meaningful discussions and brought forward exciting proposals, setting a positive and proactive tone for the project's journey ahead. What made this meeting stand out was the active involvement of consortium members even before the event. Instead of the usual approach where the kick-off meeting covers initial overviews, VICT3R partners were ready with concrete preliminary results and ideas on how to tackle the work – a testament to the passion behind our mission to reduce animal testing through Virtual Control Groups (VCGs). 💡 Key moments from the meeting include: - A strong focus on avoiding "WP silos." We took a cross-WP approach with joint sessions designed to foster collaboration and alignment across data sharing and curation, AI models and statistics, computer system validation, and other essential areas. - Lively discussions on how best to involve regulatory bodies from the project start, ensuring that VCG methodologies align with Good Laboratory Practice (GLP) standards and can be accepted in nonclinical safety assessments. 🎯 We were also delighted to have representatives from the Innovative Health Initiative (IHI) join us, providing valuable input on how VICT3R aligns with IHI’s overarching goals. The collaborative spirit during the Kick-off Meeting was truly energizing. A heartfelt thank you to all the partners and participants for your enthusiasm, hard work, and commitment. We look forward to continuing this exciting journey together! COCIR EFPIA - European Federation of Pharmaceutical Industries and Associations EuropaBio - the European Association for Bioindustries MedTech Europe Vaccines Europe Instem GRIB Barcelona PharmacoInformatics PhI SYNAPSE Research Management Partners Fraunhofer ITEM grit42 Technische Universität Dortmund PHUSE MedBioinformatics Data Analytics & Visualization Group, BSC-CNS Universität Konstanz Deciphex Organon SRL Syncwork Ag Vrije Universiteit Brussel Bayer Merck Healthcare Amgen AstraZeneca BASF Boehringer Ingelheim Bristol Myers Squibb Incyte Ipsen The Janssen Pharmaceutical Companies of Johnson & Johnson Novartis Novo Nordisk Orion Corporation Pfizer Roche Sanofi TAKEDA PHARMACEUTICALS INTERNATIONAL GMBH GLATTPARK CH UCB AbbVie
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🎉 Prof. Mathieu Vinken, #ONTOX and #ASPIS coordinator, has been granted the “Prize Dr. Monique Govaerts and Joseph Lepoix for the study of intoxications” for the research entitled “Next generation prediction of human safety of chemical compounds: liver toxicity as a case study”. 🎖Prof. Mathieu Vinken received this prestigious #award, only granted every 5 years, during an official ceremony organized by the Belgian Royal Academy for Medicine in Brussels on 28 September 2024. The awarded research has introduced a new approach to accurately predict the safety of several types of chemical compounds, including those found in biocides, food, cosmetics and pharmaceuticals, for human based on a combination of artificial intelligence and in vitro testing, and without the need of using laboratory animals. ⚗ This innovative approach has been optimized for #livertoxicity associated with the accumulation of bile acids, or so-called cholestasis, yet can be applied to any type of adversity caused by chemical compounds. This opens promising perspectives for future human-relevant and animal-free risk assessment of chemicals.
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🚨 Join the ASPIS Academy Webinar! 🚨 🗓 Date: 17 October 2024 ⏰ Time: 12:30–14:00 CET 📍 Speaker: Dr. Leonie Mueller Discover how science shapes policy and why effective communication is critical in toxicology! This engaging session, designed for early-stage researchers, offers practical insights and real-world examples of bridging the gap between science and policy. Learn about: 🔹 The growing complexity of scientific data 🔹 The challenge of communicating life sciences, particularly in toxicology 🔹 Key strategies for impactful science communication 🎯 This interactive presentation will provide you with the tools to ensure your research is understood, heard, and valued by both peers and policymakers. Don’t miss this chance to enhance your skills in science communication! Register today. 👉 More info: https://lnkd.in/eyAESBJ7 #ScienceCommunication #Toxicology #Policy #EarlyCareerResearchers #ASPIS