🎉 This month was #SNIPAFRICA 1-year anniversary! 🤔 What is the project about? ℹ️ Global Health EDCTP3 funded project, SPIN-AFRICA, is a 5-year project (2023-2028) that aims to reduce mortality among neonates in hospital with #sepsis, in #Africa. 🔬 How? 🔹 To better treat neonatal sepsis in the face of rising #antimicrobial resistance (#AMR), the project seeks to develop a #clinical #research platform for the implementation of adaptive trials in sub-Saharan Africa. 🔹 SNIP-AFRICA will conduct a trial that will identify optimal treatment regimens and doses for difficult-to-treat infections and sepsis. Check out Julia Bielicki's post below to see how much work has been done after a year of SNIP-AFRICA 👇 🥳 Congratulations to everyone involved! Check out other Global Health EDCTP3 funded projects here 👇 🔗https://lnkd.in/ez_ANRp6 ----------- European & Developing Countries Clinical Trials Partnership European Commission Africa CDC EU Science, Research and Innovation Irene Norstedt Penta Foundation - Child Health Research St George's, University of London KEMRI - Wellcome Trust UK Research and Innovation UCL Stellenbosch University Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR) Global Health and Infectious Diseases Group (GHID-KCCR) Drugs for Neglected Diseases initiative - DNDi Global Antibiotic R&D Partnership (GARDP) MU-JHU Care LTD | MU-JHU Research Collaboration Ifakara Health Institute University of Antwerp
Senior Consultant and Researcher in Paediatric Infectious Diseases in Basel (UKBB) and London (SGUL)
🌍 Africa carries a disproportionately high burden of mortality and morbidity related to #AMR with the highest attributable and associated mortality rates experienced by newborns in most African countries: https://lnkd.in/g9zARpjg #SNIPAFRICA is a Global Health EDCTP3-funded project to build a severe neonatal infection platform to address the problem of #neonatalsepsis in Africa. Our pillars are: 🏗 An adapatable infrastructure to support platform trials in severe neonatal infection. Centre for Neonatal and Paediatric Infection (CNPI), MRC Clinical Trials Unit at UCL,Penta Foundation - Child Health Research. 👩🔬 Research activities to identify best ways to use antibiotics to treat newborn babies, including pharmacokinetic studies and the #NeoSep1 trial. Stellenbosch University, Global Antibiotic R&D Partnership (GARDP), MRC Clinical Trials Unit at UCL, Kenya Medical Research Institute (KEMRI). 👨👨👧👧 Stakeholder engagement to enable successful implementation of adaptive platform trials. MU-JHU Care LTD | MU-JHU Research Collaboration, Ifakara Health Institute 📝 Capacity building and training to guarantee the local sustainability of the platform. Kwame Nkrumah University of Science and Technology, Kumasi, Penta Foundation - Child Health Research. Find out more at https://lnkd.in/gxhkNa7c One year of SNIP-AFRICA has passed and I am so impressed with everybody's work! So far, we have 👉 Set up a clinical and microbiological surveillance approach to understand the epidemiology of severe neonatal infection in Africa. 👉 Drafted templates to support dose identification and optimisation focusing on neonatal antimicrobial pharmacokinetics. 👉 Finalised the NeoSep1 protocol using a combined PRACTical and SMART design. 👉 Identified training needs and pathways towards South-South capacity building and strengthening. 👉 Moved forward with engagement activities addressing a range of stakeholders. Find below a short clip by Maxie and Damalie discussing the importance of stakeholder engagement: https://lnkd.in/gfbmnT2H