biocrates life sciences ag

Our 🌿Metabolite of the Month for July is Kynurenic acid🌿 primarily synthesized via the kynurenine pathway from dietary tryptophan. It acts as an antagonist to ionotropic glutamate receptors and has roles in neurotransmission, linking it to neurological conditions like Alzheimer's and Parkinson's disease, schizophrenia, and mood disorders. KYNA's interaction with gut microbiota influences its production, affecting neural, immune, and digestive systems. Additionally, KYNA is implicated in cancer, with varying levels found in different tumor types, and in metabolic diseases, where it helps regulate insulin sensitivity and energy homeostasis. Read more about its diverse functions and potential therapeutic applications in neurology, oncology, and metabolic health. #Metabolomics #Microbiome #LoveYourMetabolites#Guthealth

Gain firsthand insights from the biocrates team at 🌟ASMS 2024🌟 in Anaheim, CA, where over 6,000 scientists gathered for the main event in mass spectrometry. Explore their unique perspective on the conference, highlighting standardized metabolomics workflows, innovations like high-resolution metabolomics and AI applications, and the important role of quantitative mass spectrometry in advancing research and collaboration. Read our blog article : https://zurl.co/VE4f #ASMS2024 #Conference #Metabolomics #MassSpectrometry

📣New Episode- Season III of 🎧 The Metabolomist 🎧 podcast! Join Marc-Emmanuel Dumas and Alice Limonciel as they explore the crucial roles of metabolites as the communicators of the microbiome to the host, the importance of examining various aspects of the phenotype in the context of liver disease, and how machine learning and AI will transform the field in the near future. Listen now: https://zurl.co/Cu1I Subscribe to stay updated: https://zurl.co/8cid #ML #Microbiome #Podcast #Metabolomics

🎙️ The recordings from our recent ⭐Benelux Webinar: “Metabolomics – how to make the most of your data” are online now! Listen to insightful discussions on data interpretation in metabolomics, transforming statistically significant results into meaningful insights and pathways. Justin J.J. van der Hooft and Alice Limonciel share their projects and methodologies, highlighting successes and challenges in interpretation. Watch the recordings on our YouTube channel: https://zurl.co/jn0D #Metabolomics #Webinar #DataScience #Research

🌟 New 🌟 SMartIDQ alpha kit 🧪 We are happy to announce our new SMartIDQ alpha kit, designed to streamline lab operations with high-throughput capabilities and comprehensive metabolite coverage. Analyze over 100 metabolites across 13 biochemical classes using only 10 µL per sample. Compatible with various mass spectrometry platforms and sample types, this ready-to-use kit enhances your lab's efficiency and analytical power. More details: https://zurl.co/JmCg #Metabolomics #Research #Innovation #Laboratory

Feed your microbes - How diet shapes your gut microbiome On June 27th, World Microbiome Day 2024, we celebrate the fascinating world of microbes that play essential roles across our planet. Microorganisms, including bacteria, fungi, viruses, and archaea, are ubiquitous and vital to our ecosystems. 🌍 Microbiomes, communities of microorganisms, exist everywhere from soil and oceans to our own bodies. They contribute significantly to environmental health, food systems, and even human well-being by aiding digestion, producing essential nutrients, and protecting against infections. 🔬 Metabolomics research is pivotal in analyzingcan the complexities of microbiomes, revealing their functions and interactions critical to maintaining balance in our ecosystems. At biocrates we're committed to advancing metabolomics to deepen our understanding of microbiome contributions to health and sustainability. Join us in celebrating World Microbiome Day by exploring how these microscopic organisms influence everything from agriculture to climate change mitigation. Discover more about our research and its impact on microbiome science. Link in the comments. #WorldMicrobiomeDay #Microbiomes #Metabolomics #Research #Sustainability

"Our 🌿Metabolite of the Month for June is Butyric acid🌿, found in esters of animal fats and plant oils, and responsible for the foul smell of rancid butter and parmesan cheese. It is naturally synthesized through the fermentation of dietary fiber in the gut and is also industrially produced. Butyric acid plays a crucial role in the microbiome by serving as an energy source for colonic cells, influencing gut health, and modulating inflammation, which has significant implications for colorectal cancer prevention. As a signaling molecule, butyric acid impacts lipid metabolism and immune responses. It shows potential therapeutic benefits in neurological conditions, cardiometabolic diseases, and certain cancers, despite its inconsistent chemopreventive effects, known as the 'butyrate paradox'. Its multifaceted roles in gut health and disease prevention underscore its importance in scientific research and potential medical applications. . Read more about its diverse functions and potential therapeutic applications in neurological and cardiometabolic diseases in the first comment. #Metabolomics #Microbiome #LoveYourMetabolites, #Guthealth

Good news! What's new at biocrates? 🔍 SMartIDQ alpha : Enhance efficiency with this high-throughput solution, analyzing over 100 polar metabolites across 13 biochemical classes, compatible with various mass spectrometry platforms and matrices. 🔬 The 20th Annual Conference of the Metabolomics Society: June 16-20, 2024, Osaka, Japan . Meet us at table T6 126 to discuss our latest metabolomics solutions. 🧪 Metabolite of the month - Butyric acid: Explore Butyric acid's role in cardiometabolic and neurological diseases. 🤝 1st biocrates Certified Lab Day 2024 : Exclusively dedicated to our current certified laboratory partners, fostering networking and idea exchange within the metabolomics core community. For more details, check out our website: https://zurl.co/Kr40 #Metabolomics #Research #Butyric acid

The biocrates team is excited to participate in the 20th Annual Conference of the Metabolomics Society, “Metabolomics 2024,” and invites you to visit our tabletop, T6 🌟. Join Carmen Ludwig-Papst, Alice Limonciel, Marissa A. Jones, and our trusted distribution channel partner, Shigenobu Fukushima, to discuss cutting-edge advancements in metabolomics and explore collaborative opportunities. Don't miss our poster presentations, where we'll discuss the future of metabolomics with AI and showcase how our innovative approach can transform peak picking, making data analysis faster and more accurate. We look forward to meeting you! 🤝 For more information: https://lnkd.in/dcNDXUfz #MetSoc2024 #AI #Metabolomics #Conference 

Metabolite History 🌟Tryptophan🌟 📜In the early 20th century, scientists embarked on a journey that led to the discovery of tryptophan, an essential amino acid crucial for protein synthesis. From its isolation in 1901 to its synthesis and identification as a precursor to serotonin, melatonin, and niacin, tryptophan's story unfolded. However, its journey was not without hurdles, as seen in the 1980s when tryptophan supplements faced a ban due to health concerns. Despite setbacks, tryptophan's significance in biology remained profound, with its presence even found beneath the ocean floor, hinting at its role in early biological life. Intriguingly, tryptophan's fate lies in a delicate balance between biosynthesis and dietary uptake. Unable to be synthesized within the body, it must be obtained from dietary sources like dairy products, meat, and seeds. Once ingested, tryptophan undergoes catabolism primarily in the gut, influencing pathways crucial for host metabolism and immune regulation. Tryptophan's involvement extends beyond metabolism, playing a vital role in the gut-brain axis and inflammation regulation. Despite its role in various physiological processes, tryptophan remains a subject of ongoing research, with its potential therapeutic applications ranging from cardiovascular disease to cancer. Highlights: 🌟 must be obtained from dietary sources (dairy, meat, seeds) 🌟 shapes pathways essential for metabolism immune regulation 🌟 plays vital role in gut-brain axis & inflammation regulation The intricate tale of tryptophan underscores its importance in understanding human health and disease. As researchers continue to unravel its mysteries, the story of tryptophan promises to uncover new insights into the complex workings of the human body. To read more about the significance of tryptophan, follow the link in the comments. #Metabolomics #History #Science #Research