PDGFB

PDGFB
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1PDG, 3MJG, 4HQU, 4HQX, 4QCI
Identifiers
Aliases	PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis, platelet derived growth factor subunit B
External IDs	OMIM: 190040; MGI: 97528; HomoloGene: 74303; GeneCards: PDGFB; OMA:PDGFB - orthologs
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15 E1|15 37.85 cM Start 79,995,874 bp End 80,014,977 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart pancreatic ductal cell subcutaneous adipose tissue upper lobe of left lung right lobe of thyroid gland Top expressed in left lung left lung lobe More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein homodimerization activity protein heterodimerization activity chemoattractant activity platelet-derived growth factor receptor binding platelet-derived growth factor binding superoxide-generating NADPH oxidase activator activity growth factor activity identical protein binding collagen binding ربط بروتيني phosphatidylinositol-4,5-bisphosphate 3-kinase activity Cellular component platelet alpha granule lumen سيتوبلازم الفراغ خارج الخلية Golgi membrane basolateral plasma membrane cell surface endoplasmic reticulum lumen غشاء نسيج بيني خارج الخلية خارج خلوي تجويف غولجي collagen-containing extracellular matrix Biological process activation of protein kinase B activity positive regulation of DNA biosynthetic process positive regulation of chemotaxis cellular response to growth factor stimulus positive regulation of protein tyrosine kinase activity peptidyl-tyrosine phosphorylation positive regulation of cell division نماء القلب positive regulation of glomerular filtration positive regulation of mitotic nuclear division positive regulation of MAP kinase activity positive regulation of metanephric mesenchymal cell migration positive regulation of hyaluronan biosynthetic process MAPK cascade protein phosphorylation positive regulation of glomerular mesangial cell proliferation cellular response to mycophenolic acid positive regulation of fibroblast proliferation activation of protein kinase activity نمو متعدد الخلايا positive regulation of protein autophosphorylation positive regulation of reactive oxygen species metabolic process عملية التمثيل الغذائي لأنواع الأكسجين التفاعلية negative regulation of transcription, DNA-templated protein kinase C signaling metanephric glomerular mesangial cell development negative regulation of phosphatidylinositol biosynthetic process response to wounding positive regulation of phosphatidylinositol 3-kinase activity cell chemotaxis positive regulation of ERK1 and ERK2 cascade platelet degranulation ضبط زيادي للتكاثر الخلوي positive regulation of DNA replication positive regulation of gene expression embryonic placenta development تأشير نظير صماوي monocyte chemotaxis positive regulation of endothelial cell proliferation positive regulation of phosphatidylinositol 3-kinase signaling positive regulation of calcium ion import positive regulation of transcription, DNA-templated peptidyl-serine phosphorylation positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway positive regulation of blood vessel endothelial cell migration تكون الدم positive regulation of cell migration positive regulation of peptidyl-tyrosine phosphorylation extracellular matrix organization negative regulation of protein binding positive regulation of MAPK cascade positive regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of platelet activation phosphatidylinositol phosphate biosynthetic process positive regulation of vascular associated smooth muscle cell migration positive chemotaxis negative regulation of vascular associated smooth muscle cell differentiation interleukin-18-mediated signaling pathway positive regulation of pri-miRNA transcription by RNA polymerase II negative regulation of pri-miRNA transcription by RNA polymerase II negative regulation of gene expression positive regulation of smooth muscle cell migration positive regulation of smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell dedifferentiation platelet-derived growth factor receptor signaling pathway positive regulation of vascular associated smooth muscle cell proliferation negative regulation of platelet-derived growth factor receptor-beta signaling pathway regulation of signaling receptor activity positive regulation of protein kinase B signaling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5155 18591 Ensembl ENSG00000100311 ENSMUSG00000000489 UniProt P01127 P31240 RefSeq (mRNA) NM_002608، XM_047441393، XM_047441394 NM_033016، NM_002608، XM_047441393، XM_047441394 XM_006520592، XM_017316502 NM_011057، XM_006520592، XM_017316502 RefSeq (protein) NP_148937 NP_002599، NP_148937 XP_006520655، XP_030104269، XP_030104270، XP_030104271، XP_036015133، XP_036015134 NP_035187، XP_006520655، XP_030104269، XP_030104270، XP_030104271، XP_036015133، XP_036015134 Location (UCSC) n/a Chr 15: 80 – 80.01 Mb PubMed search
Wikidata
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PDGFB هوا چين موجود فى الانسان العاقل بيشفره Platelet derived growth factor subunit B.

الوظيفه

الحته دى من الصفحه دى فاضيه, ساعد ف كتابتها.

الاهميه

الحته دى من الصفحه دى فاضيه, ساعد ف كتابتها.

لينكات برانيه

• PDGFB معرف حمض نووى ريبوزى ناقل فى معرف تسلسل المرجع (الإنجليزية)
• PDGFB معرف حمض نووى ريبوزى ناقل فى معرف تسلسل المرجع (الإنجليزية)
• PDGFB معرف حمض نووى ريبوزى ناقل فى معرف تسلسل المرجع (الإنجليزية)
• PDGFB معرف حمض نووى ريبوزى ناقل فى معرف تسلسل المرجع (الإنجليزية)
• PDGFB معرف جين انتريه (الإنجليزية)
• PDGFB معرف انزمبل جين (الإنجليزية)
• PDGFB معرف نسخة انزمبل (الإنجليزية)
• PDGFB معرف نسخة انزمبل (الإنجليزية)
• PDGFB معرف نسخة انزمبل (الإنجليزية)
• PDGFB معرف نسخة انزمبل (الإنجليزية)
• PDGFB معرف قاعدة البيانات الحره (Freebase) (الإنجليزية)
• PDGFB رمز جين فى منظمة مشروع الجينوم البشرى (الإنجليزية)
• PDGFB معرف لجنة تسميات جين هوجو (الإنجليزية)
• PDGFB معرف وراثه مندليه بشريه (الإنجليزية)
• PDGFB معرف مايكروسوفت الاكاديمى (الإنجليزية)

مصادر

PDGFB على مواقع التواصل الاجتماعى

PDGFB فى المشاريع الشقيقه

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