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Varixanthone

From Wikipedia, the free encyclopedia
Varixanthone
Names
Preferred IUPAC name
(2S)-3-Hydroxy-1-[(1R,2S)-11-hydroxy-5-methyl-12-oxo-1,2,3,12-tetrahydropyrano[3,2-a]xanthen-8-yl]-3-methylbutan-2-yl formate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C26H28O8/c1-12(2)15-10-32-24-13(3)8-17-20(21(24)22(15)29)23(30)19-16(28)7-6-14(25(19)34-17)9-18(33-11-27)26(4,5)31/h6-8,11,15,18,22,28-29,31H,1,9-10H2,2-5H3/t15-,18 ,22-/m1/s1
    Key: GOKVXLNHAYUYGV-FXCLAUTBSA-N
  • CC1=CC2=C(C3=C1OC[C@@H]([C@H]3O)C(=C)C)C(=O)C4=C(C=CC(=C4O2)C[C@@H](C(C)(C)O)OC=O)O
Properties
C26H28O8
Molar mass 468.502 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Varixanthone is an antimicrobial made by the marine fungus Emericella variecolor.[2]

References

[edit]
  1. ^ "KNApSAcK Metabolite Information - C00045432". www.knapsackfamily.com.
  2. ^ Malmstrøm, J; Christophersen, C; Barrero, AF; Oltra, JE; Justicia, J; Rosales, A (March 2002). "Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor". Journal of Natural Products. 65 (3): 364–7. doi:10.1021/np0103214. PMID 11908979.