Tinyatoxin

Tinyatoxin

Names
Preferred IUPAC name [(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-2-Benzyl-6a-hydroxy-8,10-dimethyl-7-oxo-11a-(prop-1-en-2-yl)-3a,3b,6,6a,7,9a,11,11a-octahydro-2H,10H-2,9b-epoxyazuleno[5,4-e][1,3]benzodioxol-5-yl]methyl (4-hydroxyphenyl)acetate
Identifiers
CAS Number	58821-95-7 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:9603
ChemSpider	32701427
ECHA InfoCard	100.165.094
MeSH	tinyatoxin
PubChem CID	442098
UNII	WN080Z1OL0 Y
CompTox Dashboard (EPA)	DTXSID40974337
InChI InChI=1S/C36H38O8/c1-21(2)34-17-23(4)36-28(32(34)42-35(43-34,44-36)19-25-8-6-5-7-9-25)15-26(18-33(40)29(36)14-22(3)31(33)39)20-41-30(38)16-24-10-12-27(37)13-11-24/h5-15,23,28-29,32,37,40H,1,16-20H2,2-4H3/t23-,28 ,29-,32-,33-,34-,35-,36-/m1/s1 Key: WWZMXEIBZCEIFB-ACAXUWNGSA-N
SMILES C[C@@H]1C[C@]2([C@H]3[C@H]4[C@]1([C@@H]5C=C(C(=O)[C@]5(CC(=C4)COC(=O)Cc6ccc(cc6)O)O)C)O[C@](O3)(O2)Cc7ccccc7)C(=C)C
Properties
Chemical formula	C36H38O8
Molar mass	598.692 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Tinyatoxin
Heat	Above peak
Scoville scale	5,300,000,000 SHU

Tinyatoxin (TTX or TTN) is an analog of the neurotoxin resiniferatoxin. It occurs naturally in Euphorbia poissonii.

It is a neurotoxin that acts via full agonism of the vanilloid receptors of sensory nerves. Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin but is still an ultrapotent analogue of capsaicin, with a heat intensity estimate of 300 to 350 times that of capsaicin.