SUPT7L

SUPT7L
Identifiers
Aliases	SUPT7L, SPT7L, STAF65, STAF65(gamma), STAF65G, SUPT7H, SPT7-like STAGA complex gamma subunit, SPT7 like, STAGA complex gamma subunit, SPT7 like, STAGA complex subunit gamma
External IDs	OMIM: 612762; MGI: 1919445; HomoloGene: 8907; GeneCards: SUPT7L; OMA:SUPT7L - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	27,663,840 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	31,685,151 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; right uterine tube; ; anterior pituitary; ; right hemisphere of cerebellum; ; left ovary; ; apex of heart; ; right ovary; ; granulocyte; ; right lobe of thyroid gland; ; right frontal lobe;
	Top expressed in
	Rostral migratory stream; ; zygote; ; secondary oocyte; ; tail of embryo; ; ventricular zone; ; genital tubercle; ; aortic valve; ; cumulus cell; ; ascending aorta; ; proximal tubule;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; protein binding; histone acetyltransferase activity; protein heterodimerization activity;
Cellular component	nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; maintenance of protein location in nucleus; histone H3 acetylation; transcription, DNA-templated; positive regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	9913
	72195
	ENSG00000119760
	ENSMUSG00000053134
	O94864
	Q9CZV5
	NM_001282729; NM_001282730; NM_001282731; NM_001282732; NM_014860
	NM_028150
	NP_001269658; NP_001269659; NP_001269660; NP_001269661; NP_055675
	NP_082426
	Wikidata
View/Edit Human	View/Edit Mouse

STAGA complex 65 subunit gamma is a protein that in humans is encoded by the SUPT7L gene.^[5]^[6]^[7]

Interactions

SUPT7L has been shown to interact with TAF9^[6] and Transcription initiation protein SPT3 homolog.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119760 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000053134 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
^ ^a ^b ^c Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG (October 2001). "Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo". Molecular and Cellular Biology. 21 (20): 6782–95. doi:10.1128/MCB.21.20.6782-6795.2001. PMC 99856. PMID 11564863.
^ "Entrez Gene: SUPT7L suppressor of Ty 7 (S. cerevisiae)-like".

Nishizaka S, Gomi S, Harada K, Oizumi K, Itoh K, Shichijo S (September 2000). "A new tumor-rejection antigen recognized by cytotoxic T lymphocytes infiltrating into a lung adenocarcinoma". Cancer Research. 60 (17): 4830–7. PMID 10987294.
Gocke CB, Yu H, Kang J (February 2005). "Systematic identification and analysis of mammalian small ubiquitin-like modifier substrates". The Journal of Biological Chemistry. 280 (6): 5004–12. doi:10.1074/jbc.M411718200. PMID 15561718.
Wang HY, Peng G, Guo Z, Shevach EM, Wang RF (March 2005). "Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4 regulatory T cells". Journal of Immunology. 174 (5): 2661–70. doi:10.4049/jimmunol.174.5.2661. PMID 15728473.
Soutoglou E, Demény MA, Scheer E, Fienga G, Sassone-Corsi P, Tora L (May 2005). "The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners". Molecular and Cellular Biology. 25 (10): 4092–104. doi:10.1128/MCB.25.10.4092-4104.2005. PMC 1087738. PMID 15870280.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119760 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000053134 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9872452-5] Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.

[pmid11564863-6] Martinez E, Palhan VB, Tjernberg A, Lymar ES, Gamper AM, Kundu TK, Chait BT, Roeder RG (October 2001). "Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo". Molecular and Cellular Biology. 21 (20): 6782–95. doi:10.1128/MCB.21.20.6782-6795.2001. PMC 99856. PMID 11564863.

[entrez-7] "Entrez Gene: SUPT7L suppressor of Ty 7 (S. cerevisiae)-like".

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[2]

[3]

[4]

[5]

[6]

[7]

Interactions

References

Further reading