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Antimicrobial Drug Database

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Antimicrobial drug database
Content
DescriptionAMDD is the consolidation of all antimicrobial drug resources for the purpose of treating resistant microbes.
Data types
captured
Antibacteria and Antifungal drugs
OrganismsBacteria
Contact
Primary citationPMID 23317704
Access
Website[1]
Miscellaneous
Bookmarkable
entities
yes

AMDD otherwise known as Antimicrobial Drug Database is a biological database that seeks to consolidate antibacterial and antifungal drug information from a variety of sources such as PubChem, PubChem Bioassay, ZINC, ChemDB and DrugBank in order to advance the field of treatment of resistance microbes.[1][2][3][4] As of 2012, AMDD contains ~2900 antibacterial and ~1200 antifungal compounds.[1] These compounds are organized via their description, target, format, bioassay, molecular weight, hydrogen bond donor, hydrogen bond acceptor and rotatable bond. AMDD was built on Apache server 2.2.11. The function of this database is to ultimately provide a comprehensive tool that is intuitively navigated such that development of novel antibacterial and antifungal compounds are facilitated.[5]

See also

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References

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  1. ^ a b Danishuddin, Mohd; Kaushal, Lalima; Hassan Baig, Mohd; Khan, Asad U. (December 2012). "AMDD: Antimicrobial Drug Database". Genomics, Proteomics & Bioinformatics. 10 (6): 360–363. doi:10.1016/j.gpb.2012.04.002. PMC 5054706. PMID 23317704.
  2. ^ Ganz, Tomas; Lehrer, Robert I (July 1999). "Antibiotic peptides from higher eukaryotes: biology and applications". Molecular Medicine Today. 5 (7): 292–297. doi:10.1016/s1357-4310(99)01490-2. ISSN 1357-4310. PMID 10377520.
  3. ^ Irwin, John J.; Shoichet, Brian K. (January 2005). "ZINC − A Free Database of Commercially Available Compounds for Virtual Screening". Journal of Chemical Information and Modeling. 45 (1): 177–182. doi:10.1021/ci049714 . ISSN 1549-9596. PMC 1360656. PMID 15667143.
  4. ^ Chen, Jonathan; Swamidass, S. Joshua; Dou, Yimeng; Bruand, Jocelyne; Baldi, Pierre (2005-09-20). "ChemDB: a public database of small molecules and related chemoinformatics resources". Bioinformatics. 21 (22): 4133–4139. doi:10.1093/bioinformatics/bti683. ISSN 1460-2059. PMID 16174682.
  5. ^ Danishuddin, Mohd; Kaushal, Lalima; Hassan Baig, Mohd; Khan, Asad U. (December 2012). "AMDD: antimicrobial drug database". Genomics, Proteomics & Bioinformatics. 10 (6): 360–363. doi:10.1016/j.gpb.2012.04.002. ISSN 2210-3244. PMC 5054706. PMID 23317704.