23S rRNA pseudouridine2605 synthase

23S rRNA pseudouridine²⁶⁰⁵ synthase
23S rRNA pseudouridine2605 synthase
Identifiers
EC no.	5.4.99.22
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
PMC
Search
PMC	articles
PubMed	articles
NCBI	proteins

23S rRNA pseudouridine²⁶⁰⁵ synthase (EC 5.4.99.22, RluB, YciL) is an enzyme with systematic name 23S rRNA-uridine²⁶⁰⁵ uracil mutase.^[1]^[2] This enzyme catalyses the following chemical reaction

23S rRNA uridine²⁶⁰⁵

\rightleftharpoons

23S rRNA pseudouridine²⁶⁰⁵

Pseudouridine synthase RluB converts uridine²⁶⁰⁵ of 23S rRNA to pseudouridine.

References

^ Del Campo M, Kaya Y, Ofengand J (November 2001). "Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli". RNA. 7 (11): 1603–15. PMC 1370202. PMID 11720289.1603-15&rft.date=2001-11&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370202#id-name=PMC&rft_id=info:pmid/11720289&rft.aulast=Del Campo&rft.aufirst=M&rft.au=Kaya, Y&rft.au=Ofengand, J&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370202&rfr_id=info:sid/en.wikipedia.org:23S rRNA pseudouridine2605 synthase" class="Z3988">
^ Jiang M, Sullivan SM, Walker AK, Strahler JR, Andrews PC, Maddock JR (May 2007). "Identification of novel Escherichia coli ribosome-associated proteins using isobaric tags and multidimensional protein identification techniques". Journal of Bacteriology. 189 (9): 3434–44. doi:10.1128/jb.00090-07. PMC 1855874. PMID 17337586.3434-44&rft.date=2007-05&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855874#id-name=PMC&rft_id=info:pmid/17337586&rft_id=info:doi/10.1128/jb.00090-07&rft.aulast=Jiang&rft.aufirst=M&rft.au=Sullivan, SM&rft.au=Walker, AK&rft.au=Strahler, JR&rft.au=Andrews, PC&rft.au=Maddock, JR&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855874&rfr_id=info:sid/en.wikipedia.org:23S rRNA pseudouridine2605 synthase" class="Z3988">