Valerena-4,7(11)-diene synthase (EC 4.2.3.139, VoTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, valerena-4,7(11)-diene-forming).[1] This enzyme catalyses the following chemical reaction
| Valerena-4,7(11)-diene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.139 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnesyl diphosphate valerena-4,7(11)-diene diphosphate
This enzyme is isolated from the plant Valeriana officinalis (valerian).
References
edit- ^ Pyle BW, Tran HT, Pickel B, Haslam TM, Gao Z, MacNevin G, Vederas JC, Kim SU, Ro DK (September 2012). "Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis)". The FEBS Journal. 279 (17): 3136–46. doi:10.1111/j.1742-4658.2012.08692.x. PMID 22776156. S2CID 205885638.3136-46&rft.date=2012-09&rft_id=https://api.semanticscholar.org/CorpusID:205885638#id-name=S2CID&rft_id=info:pmid/22776156&rft_id=info:doi/10.1111/j.1742-4658.2012.08692.x&rft.aulast=Pyle&rft.aufirst=BW&rft.au=Tran, HT&rft.au=Pickel, B&rft.au=Haslam, TM&rft.au=Gao, Z&rft.au=MacNevin, G&rft.au=Vederas, JC&rft.au=Kim, SU&rft.au=Ro, DK&rfr_id=info:sid/en.wikipedia.org:Valerena-4,7(11)-diene synthase" class="Z3988">
External links
edit- Valerena-4,7(11)-diene synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
