Thialbarbital

Thialbarbital
Clinical data
Other names	Kemithal, 5-(1-cyclohex-2-enyl)-5-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione
ATC code	none;
Legal status
Legal status	CA: Schedule IV;
Identifiers
	IUPAC name 5-allyl-5-cyclohex-2-en-1-yl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione;
CAS Number	467-36-7 ; as salt: 3546-29-0 ;
PubChem CID	3032306;
ChemSpider	2297316 ;
UNII	ENV72C33QD; as salt: RHK739S84F ;
ChEMBL	ChEMBL2104657 ;
CompTox Dashboard (EPA)	DTXSID90861960 ;
ECHA InfoCard	100.006.720
Chemical and physical data
Formula	C13H16N2O2S
Molar mass	264.34 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1NC(=S)NC(=O)C1(C2/C=C\CCC2)C\C=C;
	InChI InChI=1S/C13H16N2O2S/c1-2-8-13(9-6-4-3-5-7-9)10(16)14-12(18)15-11(13)17/h2,4,6,9H,1,3,5,7-8H2,(H2,14,15,16,17,18) ; Key:PXLVRFQEBVNJOH-UHFFFAOYSA-N ;
	(what is this?) (verify)

Thialbarbital (Intranarcon) is a barbiturate derivative invented in the 1960s. It has sedative effects, and was used primarily for induction in surgical anaesthesia.^[1] Thialbarbital is short acting and has less of a tendency to induce respiratory depression than other barbiturate derivatives such as pentobarbital.^[2]

References

^ Golovchinsky VB, Plehotkina SI (July 1971). "Difference in the sensitivity of the cerebral cortex and midbrain reticular formation to the action of diethylether and thialbarbital". Brain Research. 30 (1): 37–47. doi:10.1016/0006-8993(71)95004-7. PMID 5092630.
^ Bercovitz AB, Godke RA, Biellier HV, Short CE (March 1975). "Surgical anesthesia in turkeys with thialbarbital sodium". American Journal of Veterinary Research. 36 (3): 301–2. PMID 1115429.

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[pmid5092630-1] Golovchinsky VB, Plehotkina SI (July 1971). "Difference in the sensitivity of the cerebral cortex and midbrain reticular formation to the action of diethylether and thialbarbital". Brain Research. 30 (1): 37–47. doi:10.1016/0006-8993(71)95004-7. PMID 5092630.

[pmid1115429-2] Bercovitz AB, Godke RA, Biellier HV, Short CE (March 1975). "Surgical anesthesia in turkeys with thialbarbital sodium". American Journal of Veterinary Research. 36 (3): 301–2. PMID 1115429.

[1]

[2]

Thialbarbital

See also

References