Talk:Acute-phase protein
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edit"inflamatory cells" on the page are neutrophils, and are the most common white blood cell in the blood in normal patients even when not experiencing a disease state. I feel thus that it is incorrect to call them such.HolyMongoose 16:18, 28 September 2006 (UTC)
Pharmacological significance
editA further clinical significance is pharmacological: the acute phase reaction response can enhance the binding of drugs: '[...] conditions resulting in the acute phase reaction response (cancer, arthritis, myocardial infarction, Crohn's disease) lead to elevated levels of α1-acid glycoprotein and enhanced binding of basic drugs.' — Wilkinson, G. R., 2001, ‘Pharmacokinetics: the Dynamics of Drug Absorption, Distribution, and Elimination’ in Hardman, J. G., and Limbird, L. E. (eds), 2001, Goldman and Gilman’s The Pharmacological Basis of Therapeutics 10th Edition, Pergamon Press, New York, pp. 3–30.
—Zoe Ocean 05:38, 16 June 2007 (UTC)
Interleukin 22?
editI don't know whether interleukin 22 merits a mention here or not. I came across one mention in passing, in a largely unrelated article: "Interleukin 22 is a cytokine involved in the acute-phase inflammatory response." [1] --Dan Wylie-Sears 2 (talk) 10:17, 16 September 2009 (UTC)
Mannose-binding protein?
editIs mannose-binding lectin really an acute-phase protein? I mean is there data that its concentration in blood increases during infection? --Kuimov (talk) 09:19, 11 December 2011 (UTC)
- It seems that hosts vary in their expression (PMID 16879241), but current reviews indicate that it is an acute-phase reactant when the genetic program is intact (full-text of these in PMC): PMID 19438602 and PMID 20636396 -- Scray (talk) 17:25, 11 December 2011 (UTC)
- OK, thanks. --Kuimov (talk) 15:34, 13 December 2011 (UTC)
IL-6
editIL6 page refers to this Wiki page. Should it be listed as well? CitizenofEarth001 (talk) 09:15, 29 May 2016 (UTC)