TJAP1

TJAP1
Identifiers
Aliases	TJAP1, PILT, TJP4, tight junction associated protein 1
External IDs	OMIM: 612658; MGI: 1921344; HomoloGene: 12534; GeneCards: TJAP1; OMA:TJAP1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	43,506,556 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	46,593,952 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; sural nerve; ; C1 segment; ; inferior ganglion of vagus nerve; ; optic nerve; ; inferior olivary nucleus; ; left ovary; ; gastrocnemius muscle; ; right ovary; ; body of uterus;
	Top expressed in
	muscle of thigh; ; ventricular zone; ; neural layer of retina; ; lip; ; vestibular sensory epithelium; ; zygote; ; gastrula; ; yolk sac; ; primary visual cortex; ; epiblast;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; cell junction; endosome; trans-Golgi network; plasma membrane; bicellular tight junction; Golgi apparatus;
Biological process	Golgi organization;
	Sources:Amigo / QuickGO
Orthologs
	93643
	74094
	ENSG00000137221
	ENSMUSG00000012296
	Q5JTD0
	Q9DCD5
NM_001146016; NM_001146017; NM_001146018; NM_001146019; NM_001146020;
	NM_080604; NM_001350561; NM_001350562; NM_001350563; NM_001350564; NM_001350565; NM_001350566; NM_001350567; NM_001350568; NM_001350569; NM_001350570; NM_001394538; NM_001394539; NM_001394540; NM_001394541; NM_001394542; NM_001394543; NM_001394544; NM_001394545
	NM_001252473; NM_001252474; NM_001252475; NM_028751
NP_001139488; NP_001139489; NP_001139490; NP_001139491; NP_001139492;
	NP_542171; NP_001337490; NP_001337491; NP_001337492; NP_001337493; NP_001337494; NP_001337495; NP_001337496; NP_001337497; NP_001337498; NP_001337499
	NP_001239402; NP_001239403; NP_001239404; NP_083027
	Wikidata
View/Edit Human	View/Edit Mouse

Tight junction-associated protein 1 is a protein that in humans is encoded by the TJAP1 gene.^[5]^[6]

Interactions

TJAP1 has been shown to interact with DLG1.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000137221 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000012296 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Kawabe H, Nakanishi H, Asada M, Fukuhara A, Morimoto K, Takeuchi M, Takai Y (Dec 2001). "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells". J Biol Chem. 276 (51): 48350–5. doi:10.1074/jbc.M107335200. PMID 11602598.48350-5&rft.date=2001-12&rft_id=info:doi/10.1074/jbc.M107335200&rft_id=info:pmid/11602598&rft.aulast=Kawabe&rft.aufirst=H&rft.au=Nakanishi, H&rft.au=Asada, M&rft.au=Fukuhara, A&rft.au=Morimoto, K&rft.au=Takeuchi, M&rft.au=Takai, Y&rft_id=https://doi.org/10.1074%2Fjbc.M107335200&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
^ "Entrez Gene: TJAP1 tight junction associated protein 1 (peripheral)".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.1–2&rft.pages=171-4&rft.date=1994&rft_id=info:doi/10.1016/0378-1119(94)90802-8&rft_id=info:pmid/8125298&rft.aulast=Maruyama&rft.aufirst=K&rft.au=Sugano, S&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.1–2&rft.pages=149-56&rft.date=1997&rft_id=info:doi/10.1016/S0378-1119(97)00411-3&rft_id=info:pmid/9373149&rft.aulast=Suzuki&rft.aufirst=Y&rft.au=Yoshitomo-Nakagawa, K&rft.au=Maruyama, K&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold, EA&rft.au=Grouse, LH&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.805-11&rft.date=2003&rft_id=info:pmid/14574404&rft_id=info:doi/10.1038/nature02055&rft_id=info:bibcode/2003Natur.425..805M&rft.aulast=Mungall&rft.aufirst=AJ&rft.au=Palmer, SA&rft.au=Sims, SK&rft_id=https://doi.org/10.1038%2Fnature02055&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.40-5&rft.date=2004&rft_id=info:doi/10.1038/ng1285&rft_id=info:pmid/14702039&rft.aulast=Ota&rft.aufirst=T&rft.au=Suzuki, Y&rft.au=Nishikawa, T&rft_id=https://doi.org/10.1038%2Fng1285&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
Xavier R, Rabizadeh S, Ishiguro K, et al. (2004). "Discs large (Dlg1) complexes in lymphocyte activation". J. Cell Biol. 166 (2): 173–8. doi:10.1083/jcb.200309044. PMC 2172307. PMID 15263016.173-8&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172307#id-name=PMC&rft_id=info:pmid/15263016&rft_id=info:doi/10.1083/jcb.200309044&rft.aulast=Xavier&rft.aufirst=R&rft.au=Rabizadeh, S&rft.au=Ishiguro, K&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172307&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.12130-5&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514446#id-name=PMC&rft_id=info:pmid/15302935&rft_id=info:doi/10.1073/pnas.0404720101&rft_id=info:bibcode/2004PNAS..10112130B&rft.aulast=Beausoleil&rft.aufirst=SA&rft.au=Jedrychowski, M&rft.au=Schwartz, D&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514446&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner, L&rft.au=Feingold, EA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000137221 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000012296 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11602598-5] Kawabe H, Nakanishi H, Asada M, Fukuhara A, Morimoto K, Takeuchi M, Takai Y (Dec 2001). "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells". J Biol Chem. 276 (51): 48350–5. doi:10.1074/jbc.M107335200. PMID 11602598.48350-5&rft.date=2001-12&rft_id=info:doi/10.1074/jbc.M107335200&rft_id=info:pmid/11602598&rft.aulast=Kawabe&rft.aufirst=H&rft.au=Nakanishi, H&rft.au=Asada, M&rft.au=Fukuhara, A&rft.au=Morimoto, K&rft.au=Takeuchi, M&rft.au=Takai, Y&rft_id=https://doi.org/10.1074%2Fjbc.M107335200&rfr_id=info:sid/en.wikipedia.org:TJAP1" class="Z3988">

[entrez-6] "Entrez Gene: TJAP1 tight junction associated protein 1 (peripheral)".

[5]

[6]

[1]

[2]

[3]

[4]

TJAP1

Interactions

References

Further reading