SOX30

SRY (sex determining region Y)-box 30 is a protein that in humans is encoded by the SOX30 gene.

Function

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

Further reading

• Koopman, P; Schepers, G; Brenner, S; Venkatesh, B (2004). "Origin and diversity of the SOX transcription factor gene family: Genome-wide analysis in Fugu rubripes". Gene. 328: 177–86. doi:10.1016/j.gene.2003.12.008. PMID 15019997.177-86&rft.date=2004&rft_id=info:doi/10.1016/j.gene.2003.12.008&rft_id=info:pmid/15019997&rft.aulast=Koopman&rft.aufirst=P&rft.au=Schepers, G&rft.au=Brenner, S&rft.au=Venkatesh, B&rfr_id=info:sid/en.wikipedia.org:SOX30" class="Z3988">
• Osaki, E; Nishina, Y; Inazawa, J; Copeland, N. G.; Gilbert, D. J.; Jenkins, N. A.; Ohsugi, M; Tezuka, T; Yoshida, M; Semba, K (1999). "Identification of a novel Sry-related gene and its germ cell-specific expression". Nucleic Acids Research. 27 (12): 2503–10. doi:10.1093/nar/27.12.2503. PMC 148454. PMID 10359848.2503-10&rft.date=1999&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC148454#id-name=PMC&rft_id=info:pmid/10359848&rft_id=info:doi/10.1093/nar/27.12.2503&rft.aulast=Osaki&rft.aufirst=E&rft.au=Nishina, Y&rft.au=Inazawa, J&rft.au=Copeland, N. G.&rft.au=Gilbert, D. J.&rft.au=Jenkins, N. A.&rft.au=Ohsugi, M&rft.au=Tezuka, T&rft.au=Yoshida, M&rft.au=Semba, K&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC148454&rfr_id=info:sid/en.wikipedia.org:SOX30" class="Z3988">
• Fan, B. J.; Wang, D. Y.; Tham, C. C.; Lam, D. S.; Pang, C. P. (2008). "Gene expression profiles of human trabecular meshwork cells induced by triamcinolone and dexamethasone". Investigative Ophthalmology & Visual Science. 49 (5): 1886–97. doi:10.1167/iovs.07-0414. PMID 18436822.1886-97&rft.date=2008&rft_id=info:doi/10.1167/iovs.07-0414&rft_id=info:pmid/18436822&rft.aulast=Fan&rft.aufirst=B. J.&rft.au=Wang, D. Y.&rft.au=Tham, C. C.&rft.au=Lam, D. S.&rft.au=Pang, C. P.&rfr_id=info:sid/en.wikipedia.org:SOX30" class="Z3988">
• Bullejos, M; Díaz de la Guardia R; Barragán, M. J.; Sánchez, A (2000). "HMG-box sequences from microbats homologous to the human SOX30 HMG-box". Genetica. 110 (2): 157–62. doi:10.1023/A:1017914005677. PMID 11678506. S2CID 16100625.157-62&rft.date=2000&rft_id=https://api.semanticscholar.org/CorpusID:16100625#id-name=S2CID&rft_id=info:pmid/11678506&rft_id=info:doi/10.1023/A:1017914005677&rft.aulast=Bullejos&rft.aufirst=M&rft.au=Díaz de la Guardia R&rft.au=Barragán, M. J.&rft.au=Sánchez, A&rfr_id=info:sid/en.wikipedia.org:SOX30" class="Z3988">

This article incorporates text from the United States National Library of Medicine, which is in the public domain.