Splicing factor, arginine/serine-rich 9, also known as SFRS9, is a human gene encoding an SR protein involved in splice site selection in alternative splicing.[5]
Interactions
editSFRS9 has been shown to interact with Y box binding protein 1[6] and NOL3.[7]
References
edit- ^ a b c GRCh38: Ensembl release 89: ENSG00000111786 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029538 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: SFRS9 splicing factor, arginine/serine-rich 9".
- ^ Raffetseder, Ute; Frye Björn; Rauen Thomas; Jürchott Karsten; Royer Hans-Dieter; Jansen Petra Lynen; Mertens Peter R (May 2003). "Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection". J. Biol. Chem. 278 (20): 18241–8. doi:10.1074/jbc.M212518200. ISSN 0021-9258. PMID 12604611.18241-8&rft.date=2003-05&rft.issn=0021-9258&rft_id=info:pmid/12604611&rft_id=info:doi/10.1074/jbc.M212518200&rft.aulast=Raffetseder&rft.aufirst=Ute&rft.au=Frye Björn&rft.au=Rauen Thomas&rft.au=Jürchott Karsten&rft.au=Royer Hans-Dieter&rft.au=Jansen Petra Lynen&rft.au=Mertens Peter R&rft_id=https://doi.org/10.1074%2Fjbc.M212518200&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- ^ Stoss, O; Schwaiger F W; Cooper T A; Stamm S (Apr 1999). "Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c". J. Biol. Chem. 274 (16): 10951–62. doi:10.1074/jbc.274.16.10951. ISSN 0021-9258. PMID 10196175.10951-62&rft.date=1999-04&rft.issn=0021-9258&rft_id=info:pmid/10196175&rft_id=info:doi/10.1074/jbc.274.16.10951&rft.aulast=Stoss&rft.aufirst=O&rft.au=Schwaiger F W&rft.au=Cooper T A&rft.au=Stamm S&rft_id=https://doi.org/10.1074%2Fjbc.274.16.10951&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
Further reading
edit- Screaton GR, Cáceres JF, Mayeda A, et al. (1995). "Identification and characterization of three members of the human SR family of pre-mRNA splicing factors". EMBO J. 14 (17): 4336–49. doi:10.1002/j.1460-2075.1995.tb00108.x. PMC 394518. PMID 7556075.4336-49&rft.date=1995&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC394518#id-name=PMC&rft_id=info:pmid/7556075&rft_id=info:doi/10.1002/j.1460-2075.1995.tb00108.x&rft.aulast=Screaton&rft.aufirst=GR&rft.au=Cáceres, JF&rft.au=Mayeda, A&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC394518&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Nayler O, Strätling W, Bourquin JP, et al. (1998). "SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements". Nucleic Acids Res. 26 (15): 3542–9. doi:10.1093/nar/26.15.3542. PMC 147731. PMID 9671816.3542-9&rft.date=1998&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC147731#id-name=PMC&rft_id=info:pmid/9671816&rft_id=info:doi/10.1093/nar/26.15.3542&rft.aulast=Nayler&rft.aufirst=O&rft.au=Strätling, W&rft.au=Bourquin, JP&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC147731&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Yuan Y; Li DM; Sun H (1998). "PIR1, a novel phosphatase that exhibits high affinity to RNA . ribonucleoprotein complexes". J. Biol. Chem. 273 (32): 20347–53. doi:10.1074/jbc.273.32.20347. PMID 9685386.20347-53&rft.date=1998&rft_id=info:doi/10.1074/jbc.273.32.20347&rft_id=info:pmid/9685386&rft.au=Yuan Y&rft.au=Li DM&rft.au=Sun H&rft_id=https://doi.org/10.1074%2Fjbc.273.32.20347&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Petersen-Mahrt SK, Estmer C, Ohrmalm C, et al. (1999). "The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation". EMBO J. 18 (4): 1014–24. doi:10.1093/emboj/18.4.1014. PMC 1171193. PMID 10022843.1014-24&rft.date=1999&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171193#id-name=PMC&rft_id=info:pmid/10022843&rft_id=info:doi/10.1093/emboj/18.4.1014&rft.aulast=Petersen-Mahrt&rft.aufirst=SK&rft.au=Estmer, C&rft.au=Ohrmalm, C&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171193&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Stoss O; Schwaiger FW; Cooper TA; Stamm S (1999). "Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c". J. Biol. Chem. 274 (16): 10951–62. doi:10.1074/jbc.274.16.10951. PMID 10196175.10951-62&rft.date=1999&rft_id=info:doi/10.1074/jbc.274.16.10951&rft_id=info:pmid/10196175&rft.au=Stoss O&rft.au=Schwaiger FW&rft.au=Cooper TA&rft.au=Stamm S&rft_id=https://doi.org/10.1074%2Fjbc.274.16.10951&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Elliott DJ, Bourgeois CF, Klink A, et al. (2000). "A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection". Proc. Natl. Acad. Sci. U.S.A. 97 (11): 5717–22. Bibcode:2000PNAS...97.5717E. doi:10.1073/pnas.97.11.5717. PMC 18499. PMID 10823932.5717-22&rft.date=2000&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC18499#id-name=PMC&rft_id=info:pmid/10823932&rft_id=info:doi/10.1073/pnas.97.11.5717&rft_id=info:bibcode/2000PNAS...97.5717E&rft.aulast=Elliott&rft.aufirst=DJ&rft.au=Bourgeois, CF&rft.au=Klink, A&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC18499&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Stoss O, Olbrich M, Hartmann AM, et al. (2001). "The STAR/GSG family protein rSLM-2 regulates the selection of alternative splice sites". J. Biol. Chem. 276 (12): 8665–73. doi:10.1074/jbc.M006851200. PMID 11118435.8665-73&rft.date=2001&rft_id=info:doi/10.1074/jbc.M006851200&rft_id=info:pmid/11118435&rft.aulast=Stoss&rft.aufirst=O&rft.au=Olbrich, M&rft.au=Hartmann, AM&rft_id=https://doi.org/10.1074%2Fjbc.M006851200&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Denegri M, Chiodi I, Corioni M, et al. (2002). "Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors". Mol. Biol. Cell. 12 (11): 3502–14. doi:10.1091/mbc.12.11.3502. PMC 60271. PMID 11694584.3502-14&rft.date=2002&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60271#id-name=PMC&rft_id=info:pmid/11694584&rft_id=info:doi/10.1091/mbc.12.11.3502&rft.aulast=Denegri&rft.aufirst=M&rft.au=Chiodi, I&rft.au=Corioni, M&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC60271&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.1-11&rft.date=2002&rft_id=https://api.semanticscholar.org/CorpusID:14132033#id-name=S2CID&rft_id=info:pmid/11790298&rft_id=info:doi/10.1016/S0960-9822(01)00650-9&rft.aulast=Andersen&rft.aufirst=JS&rft.au=Lyon, CE&rft.au=Fox, AH&rft_id=https://doi.org/10.1016%2FS0960-9822%2801%2900650-9&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Young PJ, DiDonato CJ, Hu D, et al. (2002). "SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1". Hum. Mol. Genet. 11 (5): 577–87. doi:10.1093/hmg/11.5.577. PMID 11875052.577-87&rft.date=2002&rft_id=info:doi/10.1093/hmg/11.5.577&rft_id=info:pmid/11875052&rft.aulast=Young&rft.aufirst=PJ&rft.au=DiDonato, CJ&rft.au=Hu, D&rft_id=https://doi.org/10.1093%2Fhmg%2F11.5.577&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Simard MJ; Chabot B (2002). "SRp30c is a repressor of 3' splice site utilization". Mol. Cell. Biol. 22 (12): 4001–10. doi:10.1128/MCB.22.12.4001-4010.2002. PMC 133842. PMID 12024014.4001-10&rft.date=2002&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133842#id-name=PMC&rft_id=info:pmid/12024014&rft_id=info:doi/10.1128/MCB.22.12.4001-4010.2002&rft.au=Simard MJ&rft.au=Chabot B&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133842&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold, EA&rft.au=Grouse, LH&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Raffetseder U, Frye B, Rauen T, et al. (2003). "Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection". J. Biol. Chem. 278 (20): 18241–8. doi:10.1074/jbc.M212518200. PMID 12604611.18241-8&rft.date=2003&rft_id=info:doi/10.1074/jbc.M212518200&rft_id=info:pmid/12604611&rft.aulast=Raffetseder&rft.aufirst=U&rft.au=Frye, B&rft.au=Rauen, T&rft_id=https://doi.org/10.1074%2Fjbc.M212518200&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Xu Q; Leung DY; Kisich KO (2003). "Serine-arginine-rich protein p30 directs alternative splicing of glucocorticoid receptor pre-mRNA to glucocorticoid receptor beta in neutrophils". J. Biol. Chem. 278 (29): 27112–8. doi:10.1074/jbc.M300824200. PMID 12738786.27112-8&rft.date=2003&rft_id=info:doi/10.1074/jbc.M300824200&rft_id=info:pmid/12738786&rft.au=Xu Q&rft.au=Leung DY&rft.au=Kisich KO&rft_id=https://doi.org/10.1074%2Fjbc.M300824200&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Li J, Hawkins IC, Harvey CD, et al. (2003). "Regulation of alternative splicing by SRrp86 and its interacting proteins". Mol. Cell. Biol. 23 (21): 7437–47. doi:10.1128/MCB.23.21.7437-7447.2003. PMC 207616. PMID 14559993.7437-47&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC207616#id-name=PMC&rft_id=info:pmid/14559993&rft_id=info:doi/10.1128/MCB.23.21.7437-7447.2003&rft.aulast=Li&rft.aufirst=J&rft.au=Hawkins, IC&rft.au=Harvey, CD&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC207616&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Kondo S, Yamamoto N, Murakami T, et al. (2004). "Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA". Genes Cells. 9 (2): 121–30. doi:10.1111/j.1356-9597.2004.00709.x. PMID 15009090. S2CID 22248867.121-30&rft.date=2004&rft_id=https://api.semanticscholar.org/CorpusID:22248867#id-name=S2CID&rft_id=info:pmid/15009090&rft_id=info:doi/10.1111/j.1356-9597.2004.00709.x&rft.aulast=Kondo&rft.aufirst=S&rft.au=Yamamoto, N&rft.au=Murakami, T&rft_id=https://doi.org/10.1111%2Fj.1356-9597.2004.00709.x&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.12130-5&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514446#id-name=PMC&rft_id=info:pmid/15302935&rft_id=info:doi/10.1073/pnas.0404720101&rft_id=info:bibcode/2004PNAS..10112130B&rft.aulast=Beausoleil&rft.aufirst=SA&rft.au=Jedrychowski, M&rft.au=Schwartz, D&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514446&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner, L&rft.au=Feingold, EA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Wang Y, Wang J, Gao L, et al. (2005). "Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1". J. Biol. Chem. 280 (14): 14230–9. doi:10.1074/jbc.M413846200. PMID 15695522.14230-9&rft.date=2005&rft_id=info:doi/10.1074/jbc.M413846200&rft_id=info:pmid/15695522&rft.aulast=Wang&rft.aufirst=Y&rft.au=Wang, J&rft.au=Gao, L&rft_id=https://doi.org/10.1074%2Fjbc.M413846200&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
- Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. Bibcode:2006Natur.440..346S. doi:10.1038/nature04569. PMID 16541075.346-51&rft.date=2006&rft_id=info:pmid/16541075&rft_id=info:doi/10.1038/nature04569&rft_id=info:bibcode/2006Natur.440..346S&rft.aulast=Scherer&rft.aufirst=SE&rft.au=Muzny, DM&rft.au=Buhay, CJ&rft_id=https://doi.org/10.1038%2Fnature04569&rfr_id=info:sid/en.wikipedia.org:SFRS9" class="Z3988">
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