Syntenin-2

SDCBP2
Identifiers
Aliases	SDCBP2, SITAC, SITAC18, ST-2, syndecan binding protein 2, ST2
External IDs	OMIM: 617358; MGI: 2385156; HomoloGene: 9240; GeneCards: SDCBP2; OMA:SDCBP2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	1,329,139 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	151,431,925 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; mucosa of transverse colon; ; jejunal mucosa; ; mucosa of sigmoid colon; ; pancreatic ductal cell; ; rectum; ; nasal epithelium; ; gallbladder; ; skin of leg; ; duodenum;
	Top expressed in
	mucous cell of stomach; ; pyloric antrum; ; epithelium of stomach; ; duodenum; ; intestinal villus; ; esophagus; ; jejunum; ; left colon; ; lip; ; ileum;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein C-terminus binding; protein binding; protein homodimerization activity; protein heterodimerization activity; identical protein binding; phosphatidylinositol-4,5-bisphosphate binding; lipid binding;
Cellular component	extracellular exosome; nucleus; nucleoplasm; nucleolus; cytoplasm; plasma membrane; membrane; nuclear speck;
Biological process	intracellular signal transduction; intracellular transport; nervous system development; cell population proliferation;
	Sources:Amigo / QuickGO
Orthologs
	27111
	228765
	ENSG00000125775
	ENSMUSG00000027456
	Q9H190
	Q99JZ0
	NM_080489; NM_001199784; NM_015685
	NM_145535
	NP_001186713; NP_056500; NP_536737
	NP_663510
	Wikidata
View/Edit Human	View/Edit Mouse

Syntenin-2 is a protein that in humans is encoded by the SDCBP2 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125775 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027456 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Koroll M, Rathjen FG, Volkmer H (Apr 2001). "The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity". J Biol Chem. 276 (14): 10646–54. doi:10.1074/jbc.M010647200. PMID 11152476.10646-54&rft.date=2001-04&rft_id=info:doi/10.1074/jbc.M010647200&rft_id=info:pmid/11152476&rft.aulast=Koroll&rft.aufirst=M&rft.au=Rathjen, FG&rft.au=Volkmer, H&rft_id=https://doi.org/10.1074%2Fjbc.M010647200&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
^ "Entrez Gene: SDCBP2 syndecan binding protein (syntenin) 2".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.107-13&rft.date=1996&rft_id=info:doi/10.1006/abio.1996.0138&rft_id=info:pmid/8619474&rft.aulast=Andersson&rft.aufirst=B&rft.au=Wentland, MA&rft.au=Ricafrente, JY&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.353-8&rft.date=1997&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139146#id-name=PMC&rft_id=info:pmid/9110174&rft_id=info:doi/10.1101/gr.7.4.353&rft.aulast=Yu&rft.aufirst=W&rft.au=Andersson, B&rft.au=Worley, KC&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139146&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Borrell-Pagès M, Fernández-Larrea J, Borroto A, et al. (2001). "The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein". Mol. Biol. Cell. 11 (12): 4217–25. doi:10.1091/mbc.11.12.4217. PMC 15068. PMID 11102519.4217-25&rft.date=2001&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC15068#id-name=PMC&rft_id=info:pmid/11102519&rft_id=info:doi/10.1091/mbc.11.12.4217&rft.aulast=Borrell-Pagès&rft.aufirst=M&rft.au=Fernández-Larrea, J&rft.au=Borroto, A&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC15068&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.865-71&rft.date=2002&rft_id=info:pmid/11780052&rft_id=info:doi/10.1038/414865a&rft_id=info:bibcode/2001Natur.414..865D&rft.aulast=Deloukas&rft.aufirst=P&rft.au=Matthews, LH&rft.au=Ashurst, J&rft_id=https://doi.org/10.1038%2F414865a&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.16899-903&rft.date=2003&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241#id-name=PMC&rft_id=info:pmid/12477932&rft_id=info:doi/10.1073/pnas.242603899&rft_id=info:bibcode/2002PNAS...9916899M&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold, EA&rft.au=Grouse, LH&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.40-5&rft.date=2004&rft_id=info:doi/10.1038/ng1285&rft_id=info:pmid/14702039&rft.aulast=Ota&rft.aufirst=T&rft.au=Suzuki, Y&rft.au=Nishikawa, T&rft_id=https://doi.org/10.1038%2Fng1285&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.2121-7&rft.date=2004&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928#id-name=PMC&rft_id=info:pmid/15489334&rft_id=info:doi/10.1101/gr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner, L&rft.au=Feingold, EA&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528928&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.1173-8&rft.date=2005&rft_id=info:doi/10.1038/nature04209&rft_id=https://api.semanticscholar.org/CorpusID:4427026#id-name=S2CID&rft_id=info:pmid/16189514&rft_id=info:bibcode/2005Natur.437.1173R&rft.aulast=Rual&rft.aufirst=JF&rft.au=Venkatesan, K&rft.au=Hao, T&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.55-65&rft.date=2006&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129#id-name=PMC&rft_id=info:pmid/16344560&rft_id=info:doi/10.1101/gr.4039406&rft.aulast=Kimura&rft.aufirst=K&rft.au=Wakamatsu, A&rft.au=Suzuki, Y&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125775 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027456 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11152476-5] Koroll M, Rathjen FG, Volkmer H (Apr 2001). "The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity". J Biol Chem. 276 (14): 10646–54. doi:10.1074/jbc.M010647200. PMID 11152476.10646-54&rft.date=2001-04&rft_id=info:doi/10.1074/jbc.M010647200&rft_id=info:pmid/11152476&rft.aulast=Koroll&rft.aufirst=M&rft.au=Rathjen, FG&rft.au=Volkmer, H&rft_id=https://doi.org/10.1074%2Fjbc.M010647200&rfr_id=info:sid/en.wikipedia.org:Syntenin-2" class="Z3988">

[entrez-6] "Entrez Gene: SDCBP2 syndecan binding protein (syntenin) 2".

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Syntenin-2

References

Further reading