SAMD4B

Sterile alpha motif domain containing 4B is a protein that in humans is encoded by the SAMD4B gene.

SAMD4B
Identifiers
Aliases	SAMD4B, SMGB, hSmaug2, Smaug2, sterile alpha motif domain containing 4B
External IDs	MGI: 2448542; HomoloGene: 35268; GeneCards: SAMD4B; OMA:SAMD4B - orthologs
Gene location (Human) Chr. Chromosome 19 (human) Band 19q13.2 Start 39,342,396 bp End 39,385,710 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 A3 Start 28,098,947 bp End 28,297,569 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary tibial nerve C1 segment right frontal lobe ectocervix gastric mucosa left ovary canal of the cervix right ovary anterior cingulate cortex Top expressed in genital tubercle tail of embryo gastrula granulocyte lip perirhinal cortex zygote yolk sac right ventricle superior frontal gyrus More reference expression data BioGPS n/a
Gene ontology Molecular function mRNA binding translation repressor activity RNA binding Cellular component nucleus P-body cytoplasm cytosol Biological process regulation of transcription, DNA-templated transcription, DNA-templated nuclear-transcribed mRNA poly(A) tail shortening regulation of mRNA stability negative regulation of translation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55095 233033 Ensembl ENSG00000179134 ENSMUSG00000109336 UniProt Q5PRF9 Q80XS6 RefSeq (mRNA) NM_001303614 NM_018028 NM_175021 RefSeq (protein) NP_001290543 NP_060498 n/a Location (UCSC) Chr 19: 39.34 – 39.39 Mb Chr 7: 28.1 – 28.3 Mb PubMed search
Wikidata
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Further reading

• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.628-42&rft.date=2009-11&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775832#id-name=PMC&rft_id=info:pmid/19913121&rft_id=info:doi/10.1016/j.ajhg.2009.10.014&rft.aulast=Talmud&rft.aufirst=PJ&rft.au=Drenos, F&rft.au=Shah, S&rft.au=Shah, T&rft.au=Palmen, J&rft.au=Verzilli, C&rft.au=Gaunt, TR&rft.au=Pallas, J&rft.au=Lovering, R&rft.au=Li, K&rft.au=Casas, JP&rft.au=Sofat, R&rft.au=Kumari, M&rft.au=Rodriguez, S&rft.au=Johnson, T&rft.au=Newhouse, SJ&rft.au=Dominiczak, A&rft.au=Samani, NJ&rft.au=Caulfield, M&rft.au=Sever, P&rft.au=Stanton, A&rft.au=Shields, DC&rft.au=Padmanabhan, S&rft.au=Melander, O&rft.au=Hastie, C&rft.au=Delles, C&rft.au=Ebrahim, S&rft.au=Marmot, MG&rft.au=Smith, GD&rft.au=Lawlor, DA&rft.au=Munroe, PB&rft.au=Day, IN&rft.au=Kivimaki, M&rft.au=Whittaker, J&rft.au=Humphries, SE&rft.au=Hingorani, AD&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775832&rfr_id=info:sid/en.wikipedia.org:SAMD4B" class="Z3988">
• Luo N, Li G, Li Y, Fan X, Wang Y, Ye X, Mo X, Zhou J, Yuan W, Tan M, Xie H, Ocorr K, Bodmer R, Deng Y, Wu X (May 2010). "SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity". BMB Rep. 43 (5): 355–61. doi:10.5483/bmbrep.2010.43.5.355. PMID 20510020.355-61&rft.date=2010-05&rft_id=info:doi/10.5483/bmbrep.2010.43.5.355&rft_id=info:pmid/20510020&rft.aulast=Luo&rft.aufirst=N&rft.au=Li, G&rft.au=Li, Y&rft.au=Fan, X&rft.au=Wang, Y&rft.au=Ye, X&rft.au=Mo, X&rft.au=Zhou, J&rft.au=Yuan, W&rft.au=Tan, M&rft.au=Xie, H&rft.au=Ocorr, K&rft.au=Bodmer, R&rft.au=Deng, Y&rft.au=Wu, X&rft_id=https://doi.org/10.5483%2Fbmbrep.2010.43.5.355&rfr_id=info:sid/en.wikipedia.org:SAMD4B" class="Z3988">