PRICKLE4

PRICKLE4
Identifiers
Aliases	PRICKLE4, C6orf49, OBTP, OEBT, TOMM6, prickle planar cell polarity protein 4
External IDs	OMIM: 611389; MGI: 2685785; HomoloGene: 22752; GeneCards: PRICKLE4; OMA:PRICKLE4 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	41,787,452 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	48,005,661 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; right lobe of thyroid gland; ; right hemisphere of cerebellum; ; spleen; ; left lobe of thyroid gland; ; apex of heart; ; right uterine tube; ; body of uterus; ; myometrium;
	Top expressed in
	white adipose tissue; ; muscle tissue; ; proximal tubule; ; muscle of thigh; ; quadriceps femoris muscle; ; skeletal muscle tissue; ; embryo; ; urinary bladder; ; striatum of neuraxis; ; spermatocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	zinc ion binding; metal ion binding; molecular function; actin binding; muscle alpha-actinin binding;
Cellular component	nucleus; stress fiber; Z discdkac; filamentous actin;
Biological process	biological process; heart development; actin cytoskeleton organization; muscle structure development;
	Sources:Amigo / QuickGO
Orthologs
	29964
	381104
	ENSG00000278224
	ENSMUSG00000096549
	Q2TBC4
	n/a
	NM_013397; NM_017601
	NM_001290337
	NP_037529
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Prickle-like protein 4 is a protein that in humans is encoded by the PRICKLE4 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000278224 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000096549 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Teufel A, Weinmann A, Galle PR, Lohse AW (Mar 2005). "Characterization of OEBT, a LIM protein". International Journal of Molecular Medicine. 15 (3): 513–8. doi:10.3892/ijmm.15.3.513. PMID 15702247.513-8&rft.date=2005-03&rft_id=info:doi/10.3892/ijmm.15.3.513&rft_id=info:pmid/15702247&rft.aulast=Teufel&rft.aufirst=A&rft.au=Weinmann, A&rft.au=Galle, PR&rft.au=Lohse, AW&rfr_id=info:sid/en.wikipedia.org:PRICKLE4" class="Z3988">
^ "Entrez Gene: C6orf49 chromosome 6 open reading frame 49".

External links

Human PRICKLE4 genome location and PRICKLE4 gene details page in the UCSC Genome Browser.
Human TOMM6 genome location and TOMM6 gene details page in the UCSC Genome Browser.

Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.55-65&rft.date=2006-01&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129#id-name=PMC&rft_id=info:pmid/16344560&rft_id=info:doi/10.1101/gr.4039406&rft.aulast=Kimura&rft.aufirst=K&rft.au=Wakamatsu, A&rft.au=Suzuki, Y&rft.au=Ota, T&rft.au=Nishikawa, T&rft.au=Yamashita, R&rft.au=Yamamoto, J&rft.au=Sekine, M&rft.au=Tsuritani, K&rft.au=Wakaguri, H&rft.au=Ishii, S&rft.au=Sugiyama, T&rft.au=Saito, K&rft.au=Isono, Y&rft.au=Irie, R&rft.au=Kushida, N&rft.au=Yoneyama, T&rft.au=Otsuka, R&rft.au=Kanda, K&rft.au=Yokoi, T&rft.au=Kondo, H&rft.au=Wagatsuma, M&rft.au=Murakawa, K&rft.au=Ishida, S&rft.au=Ishibashi, T&rft.au=Takahashi-Fujii, A&rft.au=Tanase, T&rft.au=Nagai, K&rft.au=Kikuchi, H&rft.au=Nakai, K&rft.au=Isogai, T&rft.au=Sugano, S&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356129&rfr_id=info:sid/en.wikipedia.org:PRICKLE4" class="Z3988">
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS, Kim NS (Dec 2005). "Transcriptome analysis of human gastric cancer". Mammalian Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.942-54&rft.date=2005-12&rft_id=https://api.semanticscholar.org/CorpusID:69278#id-name=S2CID&rft_id=info:pmid/16341674&rft_id=info:doi/10.1007/s00335-005-0075-2&rft.aulast=Oh&rft.aufirst=JH&rft.au=Yang, JO&rft.au=Hahn, Y&rft.au=Kim, MR&rft.au=Byun, SS&rft.au=Jeon, YJ&rft.au=Kim, JM&rft.au=Song, KS&rft.au=Noh, SM&rft.au=Kim, S&rft.au=Yoo, HS&rft.au=Kim, YS&rft.au=Kim, NS&rfr_id=info:sid/en.wikipedia.org:PRICKLE4" class="Z3988">
Chassin D, Bénifla JL, Delattre C, Fernandez H, Ginisty D, Janneau JL, Prade M, Contesso G, Caillou B, Tournaire M (Oct 1994). "Identification of genes overexpressed in tumors through preferential expression screening in trophoblasts". Cancer Research. 54 (19): 5217–23. PMID 7923143.5217-23&rft.date=1994-10&rft_id=info:pmid/7923143&rft.aulast=Chassin&rft.aufirst=D&rft.au=Bénifla, JL&rft.au=Delattre, C&rft.au=Fernandez, H&rft.au=Ginisty, D&rft.au=Janneau, JL&rft.au=Prade, M&rft.au=Contesso, G&rft.au=Caillou, B&rft.au=Tournaire, M&rfr_id=info:sid/en.wikipedia.org:PRICKLE4" class="Z3988">

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000278224 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000096549 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15702247-5] Teufel A, Weinmann A, Galle PR, Lohse AW (Mar 2005). "Characterization of OEBT, a LIM protein". International Journal of Molecular Medicine. 15 (3): 513–8. doi:10.3892/ijmm.15.3.513. PMID 15702247.513-8&rft.date=2005-03&rft_id=info:doi/10.3892/ijmm.15.3.513&rft_id=info:pmid/15702247&rft.aulast=Teufel&rft.aufirst=A&rft.au=Weinmann, A&rft.au=Galle, PR&rft.au=Lohse, AW&rfr_id=info:sid/en.wikipedia.org:PRICKLE4" class="Z3988">

[entrez-6] "Entrez Gene: C6orf49 chromosome 6 open reading frame 49".

[5]

[6]

[1]

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PRICKLE4

References

External links

Further reading