DNA polymerase kappa is a DNA polymerase that in humans is encoded by the POLK gene. It is involved in translesion synthesis.[4][5][6]

POLK
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPOLK, DINB1, DINP, POLQ, polymerase (DNA) kappa, DNA polymerase kappa
External IDsOMIM: 605650; MGI: 1349767; HomoloGene: 32140; GeneCards: POLK; OMA:POLK - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016218
NM_001345921
NM_001345922

NM_012048

RefSeq (protein)

NP_001332850
NP_001332851
NP_057302
NP_057302.1

NP_001334531
NP_001334532
NP_001334533
NP_001334535
NP_036178

Location (UCSC)Chr 5: 75.51 – 75.6 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000122008Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Ohashi E, Ogi T, Kusumoto R, Iwai S, Masutani C, Hanaoka F, Ohmori H (Aug 2000). "Error-prone bypass of certain DNA lesions by the human DNA polymerase κ". Genes Dev. 14 (13): 1589–94. doi:10.1101/gad.14.13.1589. PMC 316741. PMID 10887153.1589-94&rft.date=2000-08&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316741#id-name=PMC&rft_id=info:pmid/10887153&rft_id=info:doi/10.1101/gad.14.13.1589&rft.aulast=Ohashi&rft.aufirst=E&rft.au=Ogi, T&rft.au=Kusumoto, R&rft.au=Iwai, S&rft.au=Masutani, C&rft.au=Hanaoka, F&rft.au=Ohmori, H&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316741&rfr_id=info:sid/en.wikipedia.org:POLK" class="Z3988">
  5. ^ Gerlach VL, Aravind L, Gotway G, Schultz RA, Koonin EV, Friedberg EC (Nov 1999). "Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily". Proc Natl Acad Sci U S A. 96 (21): 11922–7. Bibcode:1999PNAS...9611922G. doi:10.1073/pnas.96.21.11922. PMC 18388. PMID 10518552.11922-7&rft.date=1999-11&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC18388#id-name=PMC&rft_id=info:pmid/10518552&rft_id=info:doi/10.1073/pnas.96.21.11922&rft_id=info:bibcode/1999PNAS...9611922G&rft.aulast=Gerlach&rft.aufirst=VL&rft.au=Aravind, L&rft.au=Gotway, G&rft.au=Schultz, RA&rft.au=Koonin, EV&rft.au=Friedberg, EC&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC18388&rfr_id=info:sid/en.wikipedia.org:POLK" class="Z3988">
  6. ^ "Entrez Gene: POLK Polymerase (DNA directed) kappa".

Further reading

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edit
  • Overview of all the structural information available in the PDB for UniProt: Q9UBT6 (DNA polymerase kappa) at the PDBe-KB.