The enzyme myo-inosose-2 dehydratase (EC 4.2.1.44) catalyzes the chemical reaction
| myo-inosose-2 dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.44 | ||||||||
| CAS no. | 37290-79-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- 2,4,6/3,5-pentahydroxycyclohexanone 3,5/4-trihydroxycyclohexa-1,2-dione H2O
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming). Other names in common use include inosose 2,3-dehydratase, ketoinositol dehydratase, and 2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase. This enzyme participates in inositol phosphate metabolism. It has 2 cofactors: manganese, and Cobalt.
References
edit- Berman T, Magasanik B (1966). "The pathway of myo-inositol degradation in Aerobacter aerogenes Dehydrogenation and dehydration". J. Biol. Chem. 241 (4): 800–6. PMID 5905122.800-6&rft.date=1966&rft_id=info:pmid/5905122&rft.aulast=Berman&rft.aufirst=T&rft.au=Magasanik, B&rfr_id=info:sid/en.wikipedia.org:Myo-inosose-2 dehydratase" class="Z3988">
