MYLPF

MYL11
Identifiers
Aliases	MYL11, MYLPF, myosin light chain 11, HUMMLC2B, MLC2B, myosin light chain, phosphorylatable, fast skeletal muscle, MRLC2, DA1C
External IDs	OMIM: 617378; MGI: 97273; HomoloGene: 22728; GeneCards: MYL11; OMA:MYL11 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	30,377,991 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	126,813,470 bp
RNA expression pattern
	Top expressed in
	biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; muscle of thigh; ; gastrocnemius muscle; ; vastus lateralis muscle; ; glutes; ; thoracic diaphragm; ; body of tongue;
	Top expressed in
	temporal muscle; ; sternocleidomastoid muscle; ; triceps brachii muscle; ; digastric muscle; ; medial head of gastrocnemius muscle; ; muscle of thigh; ; vastus lateralis muscle; ; body of femur; ; intercostal muscle; ; ankle;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; structural constituent of muscle; metal ion binding;
Cellular component	lysosomal membrane; cytosol; muscle myosin complex; myosin complex;
Biological process	muscle contraction; skeletal muscle tissue development; immune response;
	Sources:Amigo / QuickGO
Orthologs
	29895
	17907
	ENSG00000180209
	ENSMUSG00000030672
	Q96A32
	P97457
	NM_013292; NM_001324458; NM_001324459
	NM_016754; NM_001347655
	NP_001311387; NP_001311388; NP_037424
	NP_001334584; NP_058034
	Wikidata
View/Edit Human	View/Edit Mouse

Myosin light chain, phosphorylatable, fast skeletal muscle is a protein that in humans is encoded by the MYLPF gene.^[5] It is located on chromosome 16 in humans. Myosin light chain, phosphorylatable

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180209 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030672 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Myosin light chain, phosphorylatable, fast skeletal muscle".

Nudel U, Calvo JM, Shani M, Levy Z (Sep 1984). "The nucleotide sequence of a rat myosin light chain 2 gene". Nucleic Acids Research. 12 (18): 7175–86. doi:10.1093/nar/12.18.7175. PMC 320149. PMID 6091059.7175-86&rft.date=1984-09&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC320149#id-name=PMC&rft_id=info:pmid/6091059&rft_id=info:doi/10.1093/nar/12.18.7175&rft.aulast=Nudel&rft.aufirst=U&rft.au=Calvo, JM&rft.au=Shani, M&rft.au=Levy, Z&rft_id=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC320149&rfr_id=info:sid/en.wikipedia.org:MYLPF" class="Z3988">
Garfinkel LI, Periasamy M, Nadal-Ginard B (Sep 1982). "Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha-tropomyosin, and alpha-actin". The Journal of Biological Chemistry. 257 (18): 11078–86. doi:10.1016/S0021-9258(18)33935-8. PMID 6179945.11078-86&rft.date=1982-09&rft_id=info:doi/10.1016/S0021-9258(18)33935-8&rft_id=info:pmid/6179945&rft.aulast=Garfinkel&rft.aufirst=LI&rft.au=Periasamy, M&rft.au=Nadal-Ginard, B&rft_id=https://doi.org/10.1016%2FS0021-9258%2818%2933935-8&rfr_id=info:sid/en.wikipedia.org:MYLPF" class="Z3988">
Sachdev S, Raychowdhury MK, Sarkar S (Oct 2003). "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships". DNA Sequence. 14 (5): 339–50. doi:10.1080/1042517031000154952. PMID 14756420. S2CID 7284166.339-50&rft.date=2003-10&rft_id=https://api.semanticscholar.org/CorpusID:7284166#id-name=S2CID&rft_id=info:pmid/14756420&rft_id=info:doi/10.1080/1042517031000154952&rft.aulast=Sachdev&rft.aufirst=S&rft.au=Raychowdhury, MK&rft.au=Sarkar, S&rfr_id=info:sid/en.wikipedia.org:MYLPF" class="Z3988">
Amoresano A, Di Costanzo A, Leo G, Di Cunto F, La Mantia G, Guerrini L, Calabrò V (Apr 2010). "Identification of DeltaNp63alpha protein interactions by mass spectrometry". Journal of Proteome Research. 9 (4): 2042–8. doi:10.1021/pr9011156. PMID 20085233.2042-8&rft.date=2010-04&rft_id=info:doi/10.1021/pr9011156&rft_id=info:pmid/20085233&rft.aulast=Amoresano&rft.aufirst=A&rft.au=Di Costanzo, A&rft.au=Leo, G&rft.au=Di Cunto, F&rft.au=La Mantia, G&rft.au=Guerrini, L&rft.au=Calabrò, V&rfr_id=info:sid/en.wikipedia.org:MYLPF" class="Z3988">

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180209 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030672 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Myosin light chain, phosphorylatable, fast skeletal muscle".

[5]

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[4]

MYLPF

References

Further reading